Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Current Comment

Current Comment DERMAL ABSORPTION OF VITAMIN D Several years ago, experiments1 on rabbits and rats were reported suggesting that vitamin D was absorbed through the skin. Irradiated impure cholesterol suspended in cottonseed oil and applied to the depilated skin on the backs of the experimental animals completely protected them from rickets. Recently similar results have been obtained in rats administered viosterol by inunction. One investigator2 has observed that the application of viosterol in either a liquid petrolatum or a wax base to the tail alone permitted the absorption of sufficient amounts of the antirachitic factor to prevent the development of rickets. The possibility of the oral ingestion of some of the material was precluded by carefully encasing the animal's tail in a glass tube. Further confirmatory evidence3 has been obtained on rats fed a standard rachitogenic diet and given inunctions of viosterol in an ointment base on areas of http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

Current Comment

JAMA , Volume 105 (1) – Jul 6, 1935

Current Comment

Abstract



DERMAL ABSORPTION OF VITAMIN D
Several years ago, experiments1 on rabbits and rats were reported suggesting that vitamin D was absorbed through the skin. Irradiated impure cholesterol suspended in cottonseed oil and applied to the depilated skin on the backs of the experimental animals completely protected them from rickets. Recently similar results have been obtained in rats administered viosterol by inunction. One investigator2 has observed that the application...
Loading next page...
 
/lp/american-medical-association/current-comment-M3reUI5XIM

References (0)

References for this paper are not available at this time. We will be adding them shortly, thank you for your patience.

Publisher
American Medical Association
Copyright
Copyright © 1935 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.1935.02760270038017
Publisher site
See Article on Publisher Site

Abstract

DERMAL ABSORPTION OF VITAMIN D Several years ago, experiments1 on rabbits and rats were reported suggesting that vitamin D was absorbed through the skin. Irradiated impure cholesterol suspended in cottonseed oil and applied to the depilated skin on the backs of the experimental animals completely protected them from rickets. Recently similar results have been obtained in rats administered viosterol by inunction. One investigator2 has observed that the application of viosterol in either a liquid petrolatum or a wax base to the tail alone permitted the absorption of sufficient amounts of the antirachitic factor to prevent the development of rickets. The possibility of the oral ingestion of some of the material was precluded by carefully encasing the animal's tail in a glass tube. Further confirmatory evidence3 has been obtained on rats fed a standard rachitogenic diet and given inunctions of viosterol in an ointment base on areas of

Journal

JAMAAmerican Medical Association

Published: Jul 6, 1935

There are no references for this article.