Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Crystals in the Lens

Crystals in the Lens Abstract Crystal formation in the lens in both the young and the aged has been reported by various observers from time to time. The morphology and the chemical nature of the crystals are also of varied nature; for example, Goulden12 and other observers have described crystalline opacities in the lens showing green and blue iridescence in morbid conditions such as thyroid dysfunction, postoperative tetany, mongolian idiocy, and myotonia atrophica. Vogt26 as mentioned by Parker22 has described a "spear cataract" consisting of shiny crystalline needles. Riad24 has reported a pedigree with lens crystals which looked like tiny broken glass fragments, rectangular in shape, with a notch at one corner. Verhoeff reported a case in which protein crystals produced the picture of coralliform cataract.30 Among the varied chemical constituents of the crystals, cholesterol is frequently found in different types of senile, traumatic, and complicated cataracts. The "spear cataract" References 1. Adler, F. H.: Physiology of the Eye: Clinical Application , Henry Kimpton, London, 1950, p. 191. 2. Bensley, R. R., and Gersh, I.: Studies of Cell Structure by Freezing Drying Method: Nature of Mitochondria in Hepatic Cell of Amblyostoma , Anat. Rec. 57:217, 1933.Crossref 3. Block, R. J., and Weiss, K. W.: Amino Acid Handbook: Methods and Results of Protein Analysis , Charles C Thomas, Publisher, Springfield, Ill., 1956, p. 284. 4. Bonhag, P. F.: Histochemical Studies of the Ovarian Nurse Tissues and Oocytes of the Milkweed Bug, Oncopeltus Fasciatus: I. Cytology, Nucleic Acid and Carbohydrates , J. Morph. 96:381, 1955.Crossref 5. Bunting, H.: Histochemical Analysis of Pathological Mineral Deposits at Various Sites, with Discussion of Methods Used , A.M.A. Arch. Path. 52:458, 1951. 6. Casselman, W. G. B.: Histochemical Technique , London, Methuen & Co., Ltd., 1958, p. 149. 7. Cheng, K. K.: Experimental Studies on the Mechanism of the Zonal Distribution of Beryllium Liver Necrosis , J. Path. Bact. 71:265, 1956.Crossref 8. Cogan, D. G., and Kuwabara, T.: Ocular Pathology of Cystinosis , A.M.A. Arch. Ophthal. 63:51, 1960.Crossref 9. Cogan, D. G.; Kuwabara, T.; Kinoshita, J.; Sudarsky, D., and Ring, H.: Occular Manifestations of Systemic Cystinosis , A.M.A. Arch. Ophthal. 55:36, 1956.Crossref 10. Dahl, L. K.: Simple and Sensitive Histochemical Method for Calcium , Proc. Soc. Exp. Biol. Med. 80:474, 1952.Crossref 11. Gifford, S. R., and Puntenney, I.: Coralliform Cataract and a New Form of Congenital Cataract with Crystals in the Lens , Arch. Ophthal. 17:885, 1937.Crossref 12. Goulden, C.: Some Unusual Forms of Acquired Cataract , Trans. Ophthal. Soc. U.K. p. 97, 1928. 13. Hammett, F. S., and Chapman, S. S.: The Quantitative Unreliability of the Nitroprusside Test for -SH and -S.S- , J. Lab. Clin. Med. 24:293, 1938. 14. Hesselvik, L.: An Electrophoretic Investigation of the Proteins of the Eye Lens and the Vitreous Body , Skand. Arch. Physiol. 82:151, 1939.Crossref 15. Horawitz, W.: Methods of Analysis , Association of Official Agricultural Chemists, Ed. 8, Washington 4, D.C., 1955, p. 99. 16. Hotchkiss, R.: A Microchemical Reaction Resulting in the Staining of Polysaccharide Structures in Fixed Tissue Preparations , Arch. Biochem. 16:131, 1948. 17. Kay, W. W., and Whitehead, R.: Role of Impurities and Mixture of Isomers in Staining of Fat by Commercial Sudans , J. Path. Bact. 53:279, 1941.Crossref 18. Krause, A. C.: Chemical Pathogenesis of Cataract , Amer. J. Ophthal. 21:1343, 1938. 19. Lillie, R. D.: Personal communication to the author. 20. Lillie, R. D.: Histopathologic Technic and Practical Histochemistry , New York, Blakiston Co., 1954, p. 147. 21. Masson, P.: Some Histologic Methods: Trichrome Stainings and Their Preliminary Technique , J. Tech. Meth. 12:75, 1929. 22. Parker, C. O., Jr.: Spear Cataract , A.M.A. Arch. Ophthal. 55:23, 1956.Crossref 23. Pirie, A., and Van Heyningen, R.: Biochemistry of the Eye , Oxford, England, Blackwell Scientific Publications, pp. 14-19, 1956. 24. Riad Bey, M.: Congenital Familial Cataract with Cholesterin Deposits , Brit. J. Ophthal. 22:745, 1939.Crossref 25. Serra, J. A.: Histochemical Tests for Proteins and Amino Acids: Characterization of Basic Proteins , Stain Technol. 21:5, 1946. 26. Vogt, A.: Weitere Ergebnisse der Spaltlampenmikroskopie des vordern Bulbusabschnittes: III. Angeborene und früh erworbene Linsenveränderungen , Graefe Arch. Ophthal. 107:196, 1922. 27. Weber, A. F.; Phillips, M. G., and Bell, J. T., Jr.: An Improved Method for the Schultz Cholesterol Test , J. Histochem. Cytochem. 4:308, 1956.Crossref 28. Wolman, M.: The Lipids Stained by PAS Technic , Stain Technol. 31:241, 1956. 29. Zimmerman, L. E., and Johnson, F. B.: Calcium Oxalate Crystals Within Ocular Tissues , A.M.A. Arch. Ophthal. 60:372, 1958.Crossref 30. Verhoeff, F. H.: Microscopic Findings in a Case of Coralliform Cataract, with Remarks on Congenital Cataracts in General , Arch. Ophthal. 47:558, 1918. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Ophthalmology American Medical Association

Loading next page...
 
/lp/american-medical-association/crystals-in-the-lens-MDANeJ8Fbb
Publisher
American Medical Association
Copyright
Copyright © 1962 American Medical Association. All Rights Reserved.
ISSN
0003-9950
eISSN
1538-3687
DOI
10.1001/archopht.1962.00960030472007
Publisher site
See Article on Publisher Site

Abstract

Abstract Crystal formation in the lens in both the young and the aged has been reported by various observers from time to time. The morphology and the chemical nature of the crystals are also of varied nature; for example, Goulden12 and other observers have described crystalline opacities in the lens showing green and blue iridescence in morbid conditions such as thyroid dysfunction, postoperative tetany, mongolian idiocy, and myotonia atrophica. Vogt26 as mentioned by Parker22 has described a "spear cataract" consisting of shiny crystalline needles. Riad24 has reported a pedigree with lens crystals which looked like tiny broken glass fragments, rectangular in shape, with a notch at one corner. Verhoeff reported a case in which protein crystals produced the picture of coralliform cataract.30 Among the varied chemical constituents of the crystals, cholesterol is frequently found in different types of senile, traumatic, and complicated cataracts. The "spear cataract" References 1. Adler, F. H.: Physiology of the Eye: Clinical Application , Henry Kimpton, London, 1950, p. 191. 2. Bensley, R. R., and Gersh, I.: Studies of Cell Structure by Freezing Drying Method: Nature of Mitochondria in Hepatic Cell of Amblyostoma , Anat. Rec. 57:217, 1933.Crossref 3. Block, R. J., and Weiss, K. W.: Amino Acid Handbook: Methods and Results of Protein Analysis , Charles C Thomas, Publisher, Springfield, Ill., 1956, p. 284. 4. Bonhag, P. F.: Histochemical Studies of the Ovarian Nurse Tissues and Oocytes of the Milkweed Bug, Oncopeltus Fasciatus: I. Cytology, Nucleic Acid and Carbohydrates , J. Morph. 96:381, 1955.Crossref 5. Bunting, H.: Histochemical Analysis of Pathological Mineral Deposits at Various Sites, with Discussion of Methods Used , A.M.A. Arch. Path. 52:458, 1951. 6. Casselman, W. G. B.: Histochemical Technique , London, Methuen & Co., Ltd., 1958, p. 149. 7. Cheng, K. K.: Experimental Studies on the Mechanism of the Zonal Distribution of Beryllium Liver Necrosis , J. Path. Bact. 71:265, 1956.Crossref 8. Cogan, D. G., and Kuwabara, T.: Ocular Pathology of Cystinosis , A.M.A. Arch. Ophthal. 63:51, 1960.Crossref 9. Cogan, D. G.; Kuwabara, T.; Kinoshita, J.; Sudarsky, D., and Ring, H.: Occular Manifestations of Systemic Cystinosis , A.M.A. Arch. Ophthal. 55:36, 1956.Crossref 10. Dahl, L. K.: Simple and Sensitive Histochemical Method for Calcium , Proc. Soc. Exp. Biol. Med. 80:474, 1952.Crossref 11. Gifford, S. R., and Puntenney, I.: Coralliform Cataract and a New Form of Congenital Cataract with Crystals in the Lens , Arch. Ophthal. 17:885, 1937.Crossref 12. Goulden, C.: Some Unusual Forms of Acquired Cataract , Trans. Ophthal. Soc. U.K. p. 97, 1928. 13. Hammett, F. S., and Chapman, S. S.: The Quantitative Unreliability of the Nitroprusside Test for -SH and -S.S- , J. Lab. Clin. Med. 24:293, 1938. 14. Hesselvik, L.: An Electrophoretic Investigation of the Proteins of the Eye Lens and the Vitreous Body , Skand. Arch. Physiol. 82:151, 1939.Crossref 15. Horawitz, W.: Methods of Analysis , Association of Official Agricultural Chemists, Ed. 8, Washington 4, D.C., 1955, p. 99. 16. Hotchkiss, R.: A Microchemical Reaction Resulting in the Staining of Polysaccharide Structures in Fixed Tissue Preparations , Arch. Biochem. 16:131, 1948. 17. Kay, W. W., and Whitehead, R.: Role of Impurities and Mixture of Isomers in Staining of Fat by Commercial Sudans , J. Path. Bact. 53:279, 1941.Crossref 18. Krause, A. C.: Chemical Pathogenesis of Cataract , Amer. J. Ophthal. 21:1343, 1938. 19. Lillie, R. D.: Personal communication to the author. 20. Lillie, R. D.: Histopathologic Technic and Practical Histochemistry , New York, Blakiston Co., 1954, p. 147. 21. Masson, P.: Some Histologic Methods: Trichrome Stainings and Their Preliminary Technique , J. Tech. Meth. 12:75, 1929. 22. Parker, C. O., Jr.: Spear Cataract , A.M.A. Arch. Ophthal. 55:23, 1956.Crossref 23. Pirie, A., and Van Heyningen, R.: Biochemistry of the Eye , Oxford, England, Blackwell Scientific Publications, pp. 14-19, 1956. 24. Riad Bey, M.: Congenital Familial Cataract with Cholesterin Deposits , Brit. J. Ophthal. 22:745, 1939.Crossref 25. Serra, J. A.: Histochemical Tests for Proteins and Amino Acids: Characterization of Basic Proteins , Stain Technol. 21:5, 1946. 26. Vogt, A.: Weitere Ergebnisse der Spaltlampenmikroskopie des vordern Bulbusabschnittes: III. Angeborene und früh erworbene Linsenveränderungen , Graefe Arch. Ophthal. 107:196, 1922. 27. Weber, A. F.; Phillips, M. G., and Bell, J. T., Jr.: An Improved Method for the Schultz Cholesterol Test , J. Histochem. Cytochem. 4:308, 1956.Crossref 28. Wolman, M.: The Lipids Stained by PAS Technic , Stain Technol. 31:241, 1956. 29. Zimmerman, L. E., and Johnson, F. B.: Calcium Oxalate Crystals Within Ocular Tissues , A.M.A. Arch. Ophthal. 60:372, 1958.Crossref 30. Verhoeff, F. H.: Microscopic Findings in a Case of Coralliform Cataract, with Remarks on Congenital Cataracts in General , Arch. Ophthal. 47:558, 1918.

Journal

Archives of OphthalmologyAmerican Medical Association

Published: Oct 1, 1962

References