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Mirian Lending, L. Slobody, J. Mestern (1964)
CEREBROSPINAL FLUID GLUTAMIC OXALACETIC TRANSAMINASE AND LACTIC DEHYDROGENASE ACTIVITIES IN CHILDREN WITH NEUROLOGIC DISORDERS.The Journal of pediatrics, 65
P. Eckman, W. King, J. Brunson (1958)
Studies on the blood brain barrier. I. Effects produced by a single injection of gramnegative endotoxin on the permeability of the cerebral vessels.The American journal of pathology, 34 4
King WM Eckman PL (1958)
Studies of the blood brain barrierAmer J Path, 34
William Neches, Martin Platt (1968)
Cerebrospinal fluid LDH in 287 children, including 53 cases of meningitis of bacterial and non-bacterial etiology.Pediatrics, 41 6
N. Herschkowitz, J. Cumings (1964)
Creatine kinase in cerebrospinal fluidJournal of Neurology, Neurosurgery & Psychiatry, 27
A. Sherwin, J. Norris, J. Bulcke (1969)
Spinal fluid creatine kinase in neurologic diseaseNeurology, 19
Platt M Neches W (1968)
Cerebrospinal fluid LDH in 257 childrenPediatrics, 41
D. Dawson, I. Fine (1967)
Creatin kinase in human tissues.Archives of neurology, 16 2
D. Deul, J. Vanbreemen (1964)
ELECTROPHORESIS OF CREATINE PHOSPHOKINASE FROM VARIOUS ORGANS.Clinica chimica acta; international journal of clinical chemistry, 10
R. Lisak, F. Graig (1967)
Lack of diagnostic value of creatine phosphokinase assay in spinal fluid.JAMA, 199 10
Wolintz Ah, Engel Wk, Summers Tf (1968)
Isoenzymes of creatine phosphokinase determined by acrylamide gel electrophoresis.Journal of the Mount Sinai Hospital, New York, 35
Rosalki SB (1967)
An improved procedure for serum CPK determinationsJ Lab Clin Med, 69
H. Beaty, S. Oppenheimer (1968)
Cerebrospinal-fluid lactic dehydrogenase and its isoenzymes in infections of the central nervous system.The New England journal of medicine, 279 22
S. Rosalki (1967)
An improved procedure for serum creatine phosphokinase determination.The Journal of laboratory and clinical medicine, 69 4
Engel WK Wolintz A (1968)
Isozymes of creatine phosphokinase determined by acrylamide gel electrophoresisJ Mount Sinai Hosp NY, 35
Abstract Simultaneous creatine phosphokinase (CPK) activity in cerebrospinal fluid (CSF) and serum and with other CSF constituents was determined in children with varied central nervous system (CNS) disorders and infections. Increased CPK activity in the CNS could not be associated with CSF constituents, or with serum CPK activity. Creatinine phosphokinase elevation was noted particularly in some children with first episode of febrile seizures, and follow-up of these children revealed development of chronic degenerative brain syndromes in two. Of the afebrile seizures, only patients with major motor seizures showed consistent CPK CSF elevation as did patients with CNS neoplasms. Changes in CSF CPK levels could not be correlated with mode of onset or type of infection. It is suggested that CPK activity in the CSF is associated with CNS tissue damage or nonutilization of CPK enzyme in intracellular metabolism. References 1. Lending M, Slobody LB, Mestern J: Cerebrospinal glutamic oxalacetic transaminase and lactic dehydrogenase activity in children with neurologic disorders . J Pediat 65:415-421, 1964.Crossref 2. Beaty HN, Oppenheimer S: Cerebrospinal fluid lactic dehydrogenase and its isoenzymes in infections of the central nervous system . New Eng J Med 279:1197-1202, 1968.Crossref 3. Herschkowitz N, Cummings JW: Creatine kinase in cerebrospinal fluid . J Neurol Neurosurg Psychiat 27:247-250, 1967.Crossref 4. Neches W, Platt M: Cerebrospinal fluid LDH in 257 children . Pediatrics 41:1097-1103, 1968. 5. Sherwin AL, Norris JW, Bulcke JA: Spinal fluid creatine kinase in neurologic disease . Neurology 19:993-999, 1969.Crossref 6. Dawson D, Fine H: Creatine kinase in human tissue . Arch Neurol 16:175-180, 1967.Crossref 7. Deul DH, Van Breeman JFL: Electrophoresis of creatine phosphokinase for various organs . Clin Chim Acta 10:276-283,1964.Crossref 8. Lisak RP, Graig FA: Lack of diagnostic value of creatine phosphokinase assay in spinal fluid . JAMA 199:750-751,1967.Crossref 9. Rosalki SB: An improved procedure for serum CPK determinations . J Lab Clin Med 69:696-705,1967. 10. Wolintz A, Engel WK, Sumns TF: Isozymes of creatine phosphokinase determined by acrylamide gel electrophoresis . J Mount Sinai Hosp NY 35:174-179, 1968. 11. Eckman PL, King WM, Brienson JG: Studies of the blood brain barrier . Amer J Path 34:631-643, 1958.
American Journal of Diseases of Children – American Medical Association
Published: Dec 1, 1970
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