Key PointsQuestionIs sacubitril/valsartan cost-effective in patients with heart failure with reduced ejection fraction? FindingsWhen compared with enalapril, sacubitril/valsartan extends life, reduces hospitalizations, and has an incremental cost-effectiveness ratio of US $45 017 per quality-adjusted life-year gained in the United States. MeaningSacubitril/valsartan is cost-effective and could lead to the prevention of thousands of premature deaths and hospitalizations for patients with heart failure.
JAMA Cardiology – American Medical Association
Published: Sep 22, 2016
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