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References (9)
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A. Dorfman, K. Smull, D. Bergenstal, R. Howard, R. Muller, D. Oleson, E. Senz (1951)
Effect of adrenocorticotrophic hormone on rheumatic fever.Pediatrics, 8 5
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Hench Ps, Slocumb Ch (1949)
The effects of the adrenal cortical hormone 17-hydroxy-11-dehydrocorticosterone (Compound E) on the acute phase of rheumatic fever; preliminary report., 24
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Adams Fh (1952)
Present status of ACTH and cortisone in rheumatic fever.The Journal-lancet, 72
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E. Bland, D. Jones (1951)
Rheumatic Fever and Rheumatic Heart Disease: A Twenty Year Report on 1000 Patients Followed Since ChildhoodCirculation, 4
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A. Kuttner, J. Baldwin, C. Mcewen, J. Bunim, M. Ziff, D. Ford (1952)
Effect of ACTH and cortisone on rheumatic carditis; observations on eighteen cases.Journal of the American Medical Association, 148 8
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B. Massell, J. Warren (1950)
Effect of pituitary adrenocorticotropic hormone (ACTH) on rheumatic fever and rheumatic carditis.Journal of the American Medical Association, 144 16
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M. Wilson, H. Helper (1951)
Effect of pituitary adrenocorticotropic hormone (ACTH) in acute rheumatic carditis.Journal of the American Medical Association, 145 3
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L. Taran, G. Gulotta, N. Szilagyi, J. Jablon, W. Lane (1953)
Effect of cortisone and ACTH on the protracted phase of rheumatic carditis in children.The American journal of medicine, 14 3
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A. Barnes, H. Smith, C. Slocumb, H. Polley, P. Hench (1951)
Effect of cortisone and corticotropin (ACTH) on the acute phase of rheumatic fever; further observations.A.M.A. American journal of diseases of children, 82 4
- Publisher
- American Medical Association
- Copyright
- Copyright © 1954 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
- ISSN
- 0096-8994
- eISSN
- 1538-3628
- DOI
- 10.1001/archpedi.1954.02050090682004
- Publisher site
- See Article on Publisher Site
Abstract
SINCE 1949, when Hench1 first reported his results of the treatment of rheumatic fever with an adrenal cortex hormone, many investigators have employed cortisone and corticotropin (ACTH) to relieve both the exudative and the proliferative phases of the disease. A study of the results reported demonstrates conclusively that the exudative aspects of rheumatic fever have been satisfactorily controlled, and generally the response has been much greater and more rapid than had been obtained with salicylates. The drop to normal in temperature, the slowing of the heart rate, the diminution of the erythrocyte sedimentation rate, the elimination of pain, redness, and swelling of the joints, the return to normal of the prolonged P-R interval, the shortening of the Q-T, the suppression of abnormal antibody responses, and the reversal of the altered albumin-globulin ratio, all have responded uniformly well to hormone therapy. Unfortunately, no one has been able to state unequivocally
Journal
American journal of diseases of children – American Medical Association
Published: Jun 1, 1954