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Coronavirus Disease 2019 (COVID-19) and the Heart—Is Heart Failure the Next Chapter?

Coronavirus Disease 2019 (COVID-19) and the Heart—Is Heart Failure the Next Chapter? Opinion EDITORIAL Coronavirus Disease 2019 (COVID-19) and the Heart— Is Heart Failure the Next Chapter? Clyde W. Yancy, MD, MSc; Gregg C. Fonarow, MD Multiple data sets now confirm the increased risk for morbid Compared with controls including those with a similar pro- and mortal complications due to coronavirus disease 2019 file of preexisting conditions, left ventricular ejection frac- tion was lower and volumes higher, as well as 32% manifest- (COVID-19) in individuals with preexisting cardiovascular dis- eases including hypertension, coronary artery disease, and ing late gadolinium enhancement and 22% with pericardial 1,2 heart failure. These salient involvement. There are important residual questions about observations have strength- potential selection bias and generalizability and not all of the Related articles pages 1281 ened preventive strategies patients may have recovered, but the observations cannot be and 1265 and undoubtedly have re- dismissed. Months after a COVID-19 diagnosis, the possibility sulted in lives saved. Although episodes of clinical myocardi- exists of residual left ventricular dysfunction and ongoing tis have been suspected and a few cases have been reported inflammation, both of sufficient concern to represent a nidus in the literature, direct cardiac involvement due to the se- for new-onset heart failure and http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Cardiology American Medical Association

Coronavirus Disease 2019 (COVID-19) and the Heart—Is Heart Failure the Next Chapter?

JAMA Cardiology , Volume 5 (11) – Nov 27, 2020

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Publisher
American Medical Association
Copyright
Copyright 2020 American Medical Association. All Rights Reserved.
ISSN
2380-6583
eISSN
2380-6591
DOI
10.1001/jamacardio.2020.3575
Publisher site
See Article on Publisher Site

Abstract

Opinion EDITORIAL Coronavirus Disease 2019 (COVID-19) and the Heart— Is Heart Failure the Next Chapter? Clyde W. Yancy, MD, MSc; Gregg C. Fonarow, MD Multiple data sets now confirm the increased risk for morbid Compared with controls including those with a similar pro- and mortal complications due to coronavirus disease 2019 file of preexisting conditions, left ventricular ejection frac- tion was lower and volumes higher, as well as 32% manifest- (COVID-19) in individuals with preexisting cardiovascular dis- eases including hypertension, coronary artery disease, and ing late gadolinium enhancement and 22% with pericardial 1,2 heart failure. These salient involvement. There are important residual questions about observations have strength- potential selection bias and generalizability and not all of the Related articles pages 1281 ened preventive strategies patients may have recovered, but the observations cannot be and 1265 and undoubtedly have re- dismissed. Months after a COVID-19 diagnosis, the possibility sulted in lives saved. Although episodes of clinical myocardi- exists of residual left ventricular dysfunction and ongoing tis have been suspected and a few cases have been reported inflammation, both of sufficient concern to represent a nidus in the literature, direct cardiac involvement due to the se- for new-onset heart failure and

Journal

JAMA CardiologyAmerican Medical Association

Published: Nov 27, 2020

References