Abstract A number of surgical operations have been devised during the past 20 years for increasing blood supply to the myocardium.1 Many investigations have been performed in this field, either as experimental work on animals or as clinical studies.2 Some have claimed improvement in the clinical studies following internal mammary artery ligation.1,2 However, many workers in the field have not found improvement.3,4 The present experiments were carried out in an attempt to determine the effect of internal mammary ligation upon mortality of coronary ligation and coronary sinus return in dogs. Material and Method Trial 1. Internal Mammary Ligation. —Adult dogs of various breeds were used. They were divided evenly into 2 groups, the control and the treated groups. The control animals had their coronary arteries ligated without the preliminary ligation of internal mammary artery, while the treated ones had their internal mammary arteries ligated extrapleurally 3 weeks References 1. Chief Research Engineer, Timken Roller Bearing Company. With financial aid of the same company, Canton, Ohio. 2. Beck, C. S.: Development of a New Blood Supply to the Heart by Operation , Ann. Surg. 102:801, 1935.Crossref 3. Glover, R. P., and Davila, J. C.: Ligation of the Internal Mammary Arteries as a Means of Increasing Blood Supply to the Myocardium , J. Thor. Surg. 34:661, 1957. 4. Rowe, G. G.; Maxwell, G. M.; Castilla, C. A.; and Crumpton, C. W.; Botham, R. J., and Young, W. P.: Evaluation of Internal Mammary Artery Ligation for Angina Pectoris , Fed. Proc. 18:132, 1959. 5. DeBakey, M. E.: The Year Book of General Surgery , Chicago, Year Book Medical Publishers, Inc., 1960, p. 240. 6. Lilehei, C. W.: Direct Vision Intracardiac Surgery in Man Using a Simple Disposable Artificial Oxygenator , Dis. Chest 29:1, 1956.Crossref 7. DeWall, R. A.; Warden, H. E., and Lilehei, C. W.: Extracorporeal Circulation , Springfield, Ill., Charles C Thomas, Publisher, 1958, p. 41. 8. Markowitz, J.; Archibald, J., and Downie, H. G.: Experimental Surgery , Ed. 3, Balitmore, Williams & Wilkins Company, 1954, p. 527. 9. Sabiston, D. C., and Blalock, A.: Experimental Ligation of the Internal Mammary Artery and Its Effect on Coronary Occlusion , Surgery 43:906, 1958.
Archives of Surgery – American Medical Association
Published: Jun 1, 1962