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Corneal Endothelial Changes With Long-Term Topical Epinephrine Therapy

Corneal Endothelial Changes With Long-Term Topical Epinephrine Therapy Abstract • Corneal thicknesses and endothelial cell densities were studied in nine patients with ocular hypertension receiving long-term unilateral topical epinephrine hydrochloride therapy. No difference was noted in corneal thickness in the treated eyes. There was a significant (P <.02) reduction in endothelial cell count in the treated eyes compared to their untreated fellow controls. Those patients who had the most marked intraocular pressure response to epinephrine also had the greatest endothelial cell loss. (Arch Ophthalmol 95:1357-1358, 1977) References 1. Kolker AE, Becker B: Epinephrine maculopathy . Arch Ophthalmol 79:552-562, 1968.Crossref 2. Mishima S, Hedbes BO: Measurement of the corneal thickness with the Haag-Streit pachometer . Arch Ophthalmol 80:710-713, 1968.Crossref 3. Bourne WM, Kaufman HE: Specular microscopy of human corneal endothelium in vivo . Am J Ophthalmol 81:319-323, 1976. 4. Hull DS, Chemotti MT, Edelhauser HF, et al: Effect of epinephrine on the corneal endothelium . Am J Ophthalmol 79:245-250, 1975. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Ophthalmology American Medical Association

Corneal Endothelial Changes With Long-Term Topical Epinephrine Therapy

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Publisher
American Medical Association
Copyright
Copyright © 1977 American Medical Association. All Rights Reserved.
ISSN
0003-9950
eISSN
1538-3687
DOI
10.1001/archopht.1977.04450080067003
Publisher site
See Article on Publisher Site

Abstract

Abstract • Corneal thicknesses and endothelial cell densities were studied in nine patients with ocular hypertension receiving long-term unilateral topical epinephrine hydrochloride therapy. No difference was noted in corneal thickness in the treated eyes. There was a significant (P <.02) reduction in endothelial cell count in the treated eyes compared to their untreated fellow controls. Those patients who had the most marked intraocular pressure response to epinephrine also had the greatest endothelial cell loss. (Arch Ophthalmol 95:1357-1358, 1977) References 1. Kolker AE, Becker B: Epinephrine maculopathy . Arch Ophthalmol 79:552-562, 1968.Crossref 2. Mishima S, Hedbes BO: Measurement of the corneal thickness with the Haag-Streit pachometer . Arch Ophthalmol 80:710-713, 1968.Crossref 3. Bourne WM, Kaufman HE: Specular microscopy of human corneal endothelium in vivo . Am J Ophthalmol 81:319-323, 1976. 4. Hull DS, Chemotti MT, Edelhauser HF, et al: Effect of epinephrine on the corneal endothelium . Am J Ophthalmol 79:245-250, 1975.

Journal

Archives of OphthalmologyAmerican Medical Association

Published: Aug 1, 1977

References