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CONTACT DERMATITIS DUE TO N-ETHYL-O-CROTONOTOLUIDE OINTMENT (EURAX®)

CONTACT DERMATITIS DUE TO N-ETHYL-O-CROTONOTOLUIDE OINTMENT (EURAX®) Abstract In the past few years eurax® ointment containing 10% N-ethyl-o-crotonotoluide in a polyethylene glycol (carbowax®) base has been used as a scabicide and more recently as an antipruritic ointment. The literature reveals one report1 of sensitization to the active ingredient and several instances of sensitization to the base.2 Recently I observed a case of contact dermatitis from eurax® ointment which was due to the active principle, and because of the rarity of this finding I felt that it should be reported. REPORT OF A CASE M. C., the wife of a physician, had suffered from a pruritic recurrent eczema of the external auditory canals for many years. She had received various types of local therapy and considerable x-ray therapy in the past. During an exacerbation of her eczema, she applied curax® ointment to the external ears and to the skin around the ears References 1. Peck, S. M., and Michelfelder, T. J.: N-Ethyl-O-Crotonotoluide (Eurax) as an Antipruritic , New York J. Med. 50:1934 ( (Aug. 15) ) 1950. 2. Couperus, M. J.: The Use of N-Ethyl-O-Crotonotoluide in the Treatment of Scabies and Various Pruritic Dermatoses , J. Invest. Dermat. 13: 35 ( (July) ) 1949.Crossref 3. Goldman, L.: Recent Advances in Chemical Control of Insects : A Brief Review Connecticut M. J. 13: 624 ( (July) ) 1949. 4. Furnished through the cooperation of Geigy Company, Inc. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png A.M.A. Archives of Dermatology & Syphilology American Medical Association

CONTACT DERMATITIS DUE TO N-ETHYL-O-CROTONOTOLUIDE OINTMENT (EURAX®)

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Publisher
American Medical Association
Copyright
Copyright © 1952 American Medical Association. All Rights Reserved.
ISSN
0096-5979
DOI
10.1001/archderm.1952.01530200104019
Publisher site
See Article on Publisher Site

Abstract

Abstract In the past few years eurax® ointment containing 10% N-ethyl-o-crotonotoluide in a polyethylene glycol (carbowax®) base has been used as a scabicide and more recently as an antipruritic ointment. The literature reveals one report1 of sensitization to the active ingredient and several instances of sensitization to the base.2 Recently I observed a case of contact dermatitis from eurax® ointment which was due to the active principle, and because of the rarity of this finding I felt that it should be reported. REPORT OF A CASE M. C., the wife of a physician, had suffered from a pruritic recurrent eczema of the external auditory canals for many years. She had received various types of local therapy and considerable x-ray therapy in the past. During an exacerbation of her eczema, she applied curax® ointment to the external ears and to the skin around the ears References 1. Peck, S. M., and Michelfelder, T. J.: N-Ethyl-O-Crotonotoluide (Eurax) as an Antipruritic , New York J. Med. 50:1934 ( (Aug. 15) ) 1950. 2. Couperus, M. J.: The Use of N-Ethyl-O-Crotonotoluide in the Treatment of Scabies and Various Pruritic Dermatoses , J. Invest. Dermat. 13: 35 ( (July) ) 1949.Crossref 3. Goldman, L.: Recent Advances in Chemical Control of Insects : A Brief Review Connecticut M. J. 13: 624 ( (July) ) 1949. 4. Furnished through the cooperation of Geigy Company, Inc.

Journal

A.M.A. Archives of Dermatology & SyphilologyAmerican Medical Association

Published: Jan 1, 1952

References