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A. Qureshi, Y. Palesch, W. Barsan, D. Hanley, C. Hsu, Renee Martin, C. Moy, R. Silbergleit, T. Steiner, J. Suarez, K. Toyoda, Yongjun Wang, Haruko Yamamoto, B. Yoon (2016)
Intensive Blood-Pressure Lowering in Patients with Acute Cerebral Hemorrhage.The New England journal of medicine, 375 11
C. Anderson, E. Heeley, Yining Huang, Jiguang Wang, C. Stapf, C. Delcourt, R. Lindley, T. Robinson, P. Lavados, B. Neal, J. Hata, H. Arima, M. Parsons, Y. Li, Jinchao Wang, S. Heritier, Qiang Li, M. Woodward, R. Simes, Stephen Davis, J. Chalmers (2013)
Rapid blood-pressure lowering in patients with acute intracerebral hemorrhage.The New England journal of medicine, 368 25
A. Kelly, M. Levine (2013)
Hypocalcemia in the Critically Ill patientJournal of Intensive Care Medicine, 28
Letters NMOSDs. As clinicians, we need to weigh all the available data previous serum calcium level and corresponding BP level first to provide the best care to patients and the 26% rate of ad- before exploring the mechanism that the low serum calcium verse events, so far reported in NMOSDs, cannot be over- level after an intracerebral hemorrhage may affect the hema- looked. We think that the benefit-risk ratio should be care- toma volume through elevating BP. To our knowledge, the risk fully assessed in each patient before prescribing rituximab as of related intracerebral hemorrhage volume and expansion can a first-line therapy until randomized clinical trials provide be influenced by several regulated factors. We also notice that stronger evidence of the safety of this drug in NMOSDs. the male patients more commonly presented with hypocal- cemia on admission and the statistic of the P value was just at the critical point. Additionally, patients with hypocalcemia on Valentina Damato, MD admission were also younger than those without (mean [SD] Amelia Evoli, MD age, 68.9 [13.1] years vs 73.1 [12.4] years; P < .001). The base- Raffaele Iorio, MD, PhD line data of age and sex that determine the relationship be-
JAMA Neurology – American Medical Association
Published: Apr 13, 2017
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