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Considering Blood Pressure Level in the Association Between Serum Calcium Level and the Size and Expansion in Patients With Intracerebral Hemorrhage—Reply

Considering Blood Pressure Level in the Association Between Serum Calcium Level and the Size and... Letters NMOSDs. As clinicians, we need to weigh all the available data previous serum calcium level and corresponding BP level first to provide the best care to patients and the 26% rate of ad- before exploring the mechanism that the low serum calcium verse events, so far reported in NMOSDs, cannot be over- level after an intracerebral hemorrhage may affect the hema- looked. We think that the benefit-risk ratio should be care- toma volume through elevating BP. To our knowledge, the risk fully assessed in each patient before prescribing rituximab as of related intracerebral hemorrhage volume and expansion can a first-line therapy until randomized clinical trials provide be influenced by several regulated factors. We also notice that stronger evidence of the safety of this drug in NMOSDs. the male patients more commonly presented with hypocal- cemia on admission and the statistic of the P value was just at the critical point. Additionally, patients with hypocalcemia on Valentina Damato, MD admission were also younger than those without (mean [SD] Amelia Evoli, MD age, 68.9 [13.1] years vs 73.1 [12.4] years; P < .001). The base- Raffaele Iorio, MD, PhD line data of age and sex that determine the relationship be- http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Neurology American Medical Association

Considering Blood Pressure Level in the Association Between Serum Calcium Level and the Size and Expansion in Patients With Intracerebral Hemorrhage—Reply

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References (3)

Publisher
American Medical Association
Copyright
Copyright 2017 American Medical Association. All Rights Reserved.
ISSN
2168-6149
eISSN
2168-6157
DOI
10.1001/jamaneurol.2016.6011
pmid
28192545
Publisher site
See Article on Publisher Site

Abstract

Letters NMOSDs. As clinicians, we need to weigh all the available data previous serum calcium level and corresponding BP level first to provide the best care to patients and the 26% rate of ad- before exploring the mechanism that the low serum calcium verse events, so far reported in NMOSDs, cannot be over- level after an intracerebral hemorrhage may affect the hema- looked. We think that the benefit-risk ratio should be care- toma volume through elevating BP. To our knowledge, the risk fully assessed in each patient before prescribing rituximab as of related intracerebral hemorrhage volume and expansion can a first-line therapy until randomized clinical trials provide be influenced by several regulated factors. We also notice that stronger evidence of the safety of this drug in NMOSDs. the male patients more commonly presented with hypocal- cemia on admission and the statistic of the P value was just at the critical point. Additionally, patients with hypocalcemia on Valentina Damato, MD admission were also younger than those without (mean [SD] Amelia Evoli, MD age, 68.9 [13.1] years vs 73.1 [12.4] years; P < .001). The base- Raffaele Iorio, MD, PhD line data of age and sex that determine the relationship be-

Journal

JAMA NeurologyAmerican Medical Association

Published: Apr 13, 2017

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