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CONGENITAL MYASTHENIA GRAVIS

CONGENITAL MYASTHENIA GRAVIS MYASTHENIA gravis is rare, but does occur in the newborn. In the child of a myasthenic mother one occasionally sees the typical clinical picture. If the child survives the neonatal period, the disease disappears spontaneously in a few days or weeks. The other type of myasthenia gravis occurring in the newborn is rarer and occurs in children born of healthy mothers. Their disease resembles the adult type and tends to be permanent. It is the purpose of this communication to report such a case. REPORT OF CASE A 2-month-old white girl was admitted to the Children's Hospital on Nov. 27, 1951, for study of respiratory difficulty and inability to nurse. There was no family history of myasthenia gravis or other muscular or nervous diseases. Gestation was remarkable in that the mother was intimately exposed to an acute case poliomyelitis early in her pregnancy. Delivery was preceded by a week of http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American journal of diseases of children American Medical Association

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Publisher
American Medical Association
Copyright
Copyright © 1953 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0096-8994
eISSN
1538-3628
DOI
10.1001/archpedi.1953.02050080207008
Publisher site
See Article on Publisher Site

Abstract

MYASTHENIA gravis is rare, but does occur in the newborn. In the child of a myasthenic mother one occasionally sees the typical clinical picture. If the child survives the neonatal period, the disease disappears spontaneously in a few days or weeks. The other type of myasthenia gravis occurring in the newborn is rarer and occurs in children born of healthy mothers. Their disease resembles the adult type and tends to be permanent. It is the purpose of this communication to report such a case. REPORT OF CASE A 2-month-old white girl was admitted to the Children's Hospital on Nov. 27, 1951, for study of respiratory difficulty and inability to nurse. There was no family history of myasthenia gravis or other muscular or nervous diseases. Gestation was remarkable in that the mother was intimately exposed to an acute case poliomyelitis early in her pregnancy. Delivery was preceded by a week of

Journal

American journal of diseases of childrenAmerican Medical Association

Published: Aug 1, 1953

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