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Congenital Hyperkeratotic Papules in a 15-Year-Old Girl—Quiz Case

Congenital Hyperkeratotic Papules in a 15-Year-Old Girl—Quiz Case Report of a case A 15-year-old African American girl was referred to our clinic for evaluation of untreated multiple papules and plaques on her hands and feet that had been present since birth. She occasionally bit the lesions. She had no history of excessive sun exposure or hyperhidrosis, but her father had similar lesions. Physical examination revealed multiple crateriform hyperkeratotic papules located primarily at the boundary of the dorsal and plantar surfaces of the patient's hands (Figure 1) and feet. She also had hypopigmented, hyperkeratotic plaques overlying the distal interphalangeal and proximal interphalangeal and metacarpophalangeal joints of both hands (Figure 2), as well as the distal and proximal interphalangeal and metatarsophalangeal joints of both feet. Figure 1. View LargeDownload Figure 2. View LargeDownload A 4-mm punch biopsy specimen was obtained from a plaque overlying the third proximal interphalangeal joint on the left hand and a 2-mm punch biopsy specimen from a papule on the lateral border of the left hand (Figure 3). Figure 3. View LargeDownload What is your diagnosis? http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

Congenital Hyperkeratotic Papules in a 15-Year-Old Girl—Quiz Case

Archives of Dermatology , Volume 140 (4) – Apr 1, 2004

Congenital Hyperkeratotic Papules in a 15-Year-Old Girl—Quiz Case

Abstract

Report of a case A 15-year-old African American girl was referred to our clinic for evaluation of untreated multiple papules and plaques on her hands and feet that had been present since birth. She occasionally bit the lesions. She had no history of excessive sun exposure or hyperhidrosis, but her father had similar lesions. Physical examination revealed multiple crateriform hyperkeratotic papules located primarily at the boundary of the dorsal and plantar surfaces of the patient's hands...
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Publisher
American Medical Association
Copyright
Copyright © 2004 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.140.4.479-e
Publisher site
See Article on Publisher Site

Abstract

Report of a case A 15-year-old African American girl was referred to our clinic for evaluation of untreated multiple papules and plaques on her hands and feet that had been present since birth. She occasionally bit the lesions. She had no history of excessive sun exposure or hyperhidrosis, but her father had similar lesions. Physical examination revealed multiple crateriform hyperkeratotic papules located primarily at the boundary of the dorsal and plantar surfaces of the patient's hands (Figure 1) and feet. She also had hypopigmented, hyperkeratotic plaques overlying the distal interphalangeal and proximal interphalangeal and metacarpophalangeal joints of both hands (Figure 2), as well as the distal and proximal interphalangeal and metatarsophalangeal joints of both feet. Figure 1. View LargeDownload Figure 2. View LargeDownload A 4-mm punch biopsy specimen was obtained from a plaque overlying the third proximal interphalangeal joint on the left hand and a 2-mm punch biopsy specimen from a papule on the lateral border of the left hand (Figure 3). Figure 3. View LargeDownload What is your diagnosis?

Journal

Archives of DermatologyAmerican Medical Association

Published: Apr 1, 2004

Keywords: keratosis,papule

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