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Congenital Heart Disease and Neuroblastoma: Case Report and Brief Comment

Congenital Heart Disease and Neuroblastoma: Case Report and Brief Comment Abstract RECENTLY several reports have appeared linking neuroblastomas (or more highly differentiated neural crest tumors) with congenital heart disease.1-3 The following case is reported to add an additional instance of associated congenital heart disease and in situ neuroblastoma to the literature, and to focus further attention on this unusual relationship. Report of Case A male infant weighing 3.95 kg (8 lb 11 oz) was born at the Kaiser Foundation Hospital in Los Angeles on Feb 14, 1964, to a 25-year-old mother following a full-term, uneventful pregnancy. The initial Apgar rating was 8, and no abnormalities were noted upon routine pediatric examination. The nursery stay was unremarkable and the infant was discharged with the mother after three days. There were two older normal siblings, and no history of congenital heart disease in the family.The infant was seen at 4 weeks of age, weighing 4.1 kg (9 lb) and no abnormalities References 1. Beckwith, J.B., and Perrin, E.V.: In Situ Neuroblastomas: A contribution to the Natural History of Neural Crest Tumors , Amer J Path 43:1089, 1963. 2. Folger, G.M., et al: Cyanotic Malformations of the Heart With Pheochromocytoma , Circulation 29:750, 1964.Crossref 3. Roberts, W.C.; Mason, D.T.; and Braunwald, E.: Survival to Adulthood in a Patient With Complete Transposition of the Great Vessels, Including a Note on the Association of Endocrine Tumors With Heart Disease , Ann Intern Med 57:834, 1962.Crossref 4. Bartter, F.C., et al: Problem in Differential Diagnosis: Clinical Pathological Conference at the National Institutes of Health , Ann Intern Med 52:1289, 1960.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Diseases of Children American Medical Association

Congenital Heart Disease and Neuroblastoma: Case Report and Brief Comment

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Publisher
American Medical Association
Copyright
Copyright © 1966 American Medical Association. All Rights Reserved.
ISSN
0002-922X
DOI
10.1001/archpedi.1966.02090060118016
Publisher site
See Article on Publisher Site

Abstract

Abstract RECENTLY several reports have appeared linking neuroblastomas (or more highly differentiated neural crest tumors) with congenital heart disease.1-3 The following case is reported to add an additional instance of associated congenital heart disease and in situ neuroblastoma to the literature, and to focus further attention on this unusual relationship. Report of Case A male infant weighing 3.95 kg (8 lb 11 oz) was born at the Kaiser Foundation Hospital in Los Angeles on Feb 14, 1964, to a 25-year-old mother following a full-term, uneventful pregnancy. The initial Apgar rating was 8, and no abnormalities were noted upon routine pediatric examination. The nursery stay was unremarkable and the infant was discharged with the mother after three days. There were two older normal siblings, and no history of congenital heart disease in the family.The infant was seen at 4 weeks of age, weighing 4.1 kg (9 lb) and no abnormalities References 1. Beckwith, J.B., and Perrin, E.V.: In Situ Neuroblastomas: A contribution to the Natural History of Neural Crest Tumors , Amer J Path 43:1089, 1963. 2. Folger, G.M., et al: Cyanotic Malformations of the Heart With Pheochromocytoma , Circulation 29:750, 1964.Crossref 3. Roberts, W.C.; Mason, D.T.; and Braunwald, E.: Survival to Adulthood in a Patient With Complete Transposition of the Great Vessels, Including a Note on the Association of Endocrine Tumors With Heart Disease , Ann Intern Med 57:834, 1962.Crossref 4. Bartter, F.C., et al: Problem in Differential Diagnosis: Clinical Pathological Conference at the National Institutes of Health , Ann Intern Med 52:1289, 1960.Crossref

Journal

American Journal of Diseases of ChildrenAmerican Medical Association

Published: Mar 1, 1966

References