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CONGENITAL ESSENTIAL THROMBOPENIC PURPURA

CONGENITAL ESSENTIAL THROMBOPENIC PURPURA As a preliminary to reporting this case of congenital thrombopenic purpura, it seemed pertinent to review the literature in order to determine whether the criteria for a correct diagnosis had been fulfilled in every instance of so-called congenital thrombopenic purpura. Perusal of the literature revealed the fact that thirteen observers had reported cases of this disease. These cases were scrutinized carefully, observing the criteria which will be noted here. Since the advent of new procedures, in the last decade, finer methods of study in the hemorrhagic tendencies have been utilized. These include study of the megakaryocytes in the bone marrow and estimation of the prothrombin level. In all fairness to previous reports, diagnosis made by authors without benefit of bone marrow and prothrombin determinations have been accepted if the rest of the findings made the diagnosis plausible. In the future, however, much can be gained by adhering to the criteria http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American journal of diseases of children American Medical Association

CONGENITAL ESSENTIAL THROMBOPENIC PURPURA

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Publisher
American Medical Association
Copyright
Copyright © 1945 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0096-8994
eISSN
1538-3628
DOI
10.1001/archpedi.1945.02020200059008
Publisher site
See Article on Publisher Site

Abstract

As a preliminary to reporting this case of congenital thrombopenic purpura, it seemed pertinent to review the literature in order to determine whether the criteria for a correct diagnosis had been fulfilled in every instance of so-called congenital thrombopenic purpura. Perusal of the literature revealed the fact that thirteen observers had reported cases of this disease. These cases were scrutinized carefully, observing the criteria which will be noted here. Since the advent of new procedures, in the last decade, finer methods of study in the hemorrhagic tendencies have been utilized. These include study of the megakaryocytes in the bone marrow and estimation of the prothrombin level. In all fairness to previous reports, diagnosis made by authors without benefit of bone marrow and prothrombin determinations have been accepted if the rest of the findings made the diagnosis plausible. In the future, however, much can be gained by adhering to the criteria

Journal

American journal of diseases of childrenAmerican Medical Association

Published: Aug 1, 1945

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