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Congenital Asymmetry, Short Stature, and Elevated Urinary Gonadotropin

Congenital Asymmetry, Short Stature, and Elevated Urinary Gonadotropin Abstract In 1953 we1 first described the "Syndrome of Congenital Hemihypertrophy, Shortness of Stature, and Elevated Urinary Gonadotropins" in two children, a girl aged 5½ years and a boy 6 years old. Subsequently Silver and Gruskay2 reported a case of hemihypertrophy and elevated urinary gonadotropin in a 7-year-old boy with normal height. In none of these cases was there any other evidence of apparent endocrine disturbance. The purpose of this paper is to report two additional cases of this syndrome: the first in an 8½-year-old Negro boy with shortness of stature and elevated urinary gonadotropins in whom the difference in the two sides of the body was limited to the spine, and the other in an 8-month-old white boy with shortness of stature, a difference in size of the legs, and swelling of the dorsa of the hands and feet. A tabulation of the findings in these five cases References 1. Silver, H. K.; Kiyasu, W.; George, J., and Deamer, W. C.: Syndrome of Congenital Hemihypertrophy, Shortness of Stature, and Elevated Urinary Gonadotropins , Pediatrics 12:368, 1953. 2. Silver, H. K., and Gruskay, F. L.: Syndrome of Congenital Hemihypertrophy and Elevated Urinary Gonadotropins: Occurrence in a Seven-Year-Old Boy , A. M. A. J. Dis. Child. 93:559, 1957.Crossref 3. Ward, J., and Lerner, H. H.: Review of Subject of Congenital Hemihypertrophy and Complete Case Report , J. Pediat. 31:403, 1947.Crossref 4. Russell, A.: A Syndrome of "Intra-Uterine" Dwarfism Recognizable at Birth with Cranio Facial Dysostosis, Disproportionately Short Arms, and Other Anomalies (5 Examples) , Proc. Roy. Soc. Med. 47:1040, 1954. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png A.M.A. Journal of Diseases of Children American Medical Association

Congenital Asymmetry, Short Stature, and Elevated Urinary Gonadotropin

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Publisher
American Medical Association
Copyright
Copyright © 1959 American Medical Association. All Rights Reserved.
ISSN
0096-6916
DOI
10.1001/archpedi.1959.02070010770002
Publisher site
See Article on Publisher Site

Abstract

Abstract In 1953 we1 first described the "Syndrome of Congenital Hemihypertrophy, Shortness of Stature, and Elevated Urinary Gonadotropins" in two children, a girl aged 5½ years and a boy 6 years old. Subsequently Silver and Gruskay2 reported a case of hemihypertrophy and elevated urinary gonadotropin in a 7-year-old boy with normal height. In none of these cases was there any other evidence of apparent endocrine disturbance. The purpose of this paper is to report two additional cases of this syndrome: the first in an 8½-year-old Negro boy with shortness of stature and elevated urinary gonadotropins in whom the difference in the two sides of the body was limited to the spine, and the other in an 8-month-old white boy with shortness of stature, a difference in size of the legs, and swelling of the dorsa of the hands and feet. A tabulation of the findings in these five cases References 1. Silver, H. K.; Kiyasu, W.; George, J., and Deamer, W. C.: Syndrome of Congenital Hemihypertrophy, Shortness of Stature, and Elevated Urinary Gonadotropins , Pediatrics 12:368, 1953. 2. Silver, H. K., and Gruskay, F. L.: Syndrome of Congenital Hemihypertrophy and Elevated Urinary Gonadotropins: Occurrence in a Seven-Year-Old Boy , A. M. A. J. Dis. Child. 93:559, 1957.Crossref 3. Ward, J., and Lerner, H. H.: Review of Subject of Congenital Hemihypertrophy and Complete Case Report , J. Pediat. 31:403, 1947.Crossref 4. Russell, A.: A Syndrome of "Intra-Uterine" Dwarfism Recognizable at Birth with Cranio Facial Dysostosis, Disproportionately Short Arms, and Other Anomalies (5 Examples) , Proc. Roy. Soc. Med. 47:1040, 1954.

Journal

A.M.A. Journal of Diseases of ChildrenAmerican Medical Association

Published: Jun 1, 1959

References