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Complications of Diuretics

Complications of Diuretics To the Editor.— Many favorable comments have come from readers of the CLINICAL CARDIOLOGY series sponsored in The Journal by the American Heart Association. The readers find the articles to be practical, succinct, and generally complete. On the last point, the article "How to Avoid Complications of Potent Diuretics" (235:2526, 1976) failed to mention possible clinically important adverse effects of diuretics on calcium and magnesium excretion. As a ready source of reference, an editorial in the British Medical Journal (1:170, 1975) notes that long-term administration of diuretics may cause either hypocalcemia or hypercalcemia, depending on the type of diuretic administered. More important, the thiazide diuretics and furosemide tend to deplete body magnesium stores, thereby producing symptoms of hypomagnesemia (predisposition to ventricular premature contractions, exacerbation of digitalis toxicity, muscular cramps, paresthesias, nausea, and vomiting). The editorial concludes: "Perhaps in the not too distant future we shall be giving our patients on diuretics http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

Complications of Diuretics

Hussey, Hugh H.
JAMA , Volume 236 (7) – Aug 16, 1976
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Complications of Diuretics

Abstract



To the Editor.—
Many favorable comments have come from readers of the CLINICAL CARDIOLOGY series sponsored in The Journal by the American Heart Association. The readers find the articles to be practical, succinct, and generally complete. On the last point, the article "How to Avoid Complications of Potent Diuretics" (235:2526, 1976) failed to mention possible clinically important adverse effects of diuretics on calcium and magnesium excretion.
As a ready source of reference,...
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Publisher
American Medical Association
Copyright
Copyright © 1976 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.1976.03270080012006
Publisher site
See Article on Publisher Site

Abstract

To the Editor.— Many favorable comments have come from readers of the CLINICAL CARDIOLOGY series sponsored in The Journal by the American Heart Association. The readers find the articles to be practical, succinct, and generally complete. On the last point, the article "How to Avoid Complications of Potent Diuretics" (235:2526, 1976) failed to mention possible clinically important adverse effects of diuretics on calcium and magnesium excretion. As a ready source of reference, an editorial in the British Medical Journal (1:170, 1975) notes that long-term administration of diuretics may cause either hypocalcemia or hypercalcemia, depending on the type of diuretic administered. More important, the thiazide diuretics and furosemide tend to deplete body magnesium stores, thereby producing symptoms of hypomagnesemia (predisposition to ventricular premature contractions, exacerbation of digitalis toxicity, muscular cramps, paresthesias, nausea, and vomiting). The editorial concludes: "Perhaps in the not too distant future we shall be giving our patients on diuretics

Journal

JAMA – American Medical Association

Published: Aug 16, 1976

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