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COMPARISON OF RESULTS OF CORTISONE TREATMENT BY INSTILLATION AND BY SUBCONJUNCTIVAL INJECTION: An Experimental Study

COMPARISON OF RESULTS OF CORTISONE TREATMENT BY INSTILLATION AND BY SUBCONJUNCTIVAL INJECTION: An... Abstract AS TOPICAL therapy for diseases of the cornea, cortisone is frequently given, either by instillation or by subconjunctival injection. Among the effects which cortisone may have on the diseased cornea is the inhibition of new vascularization. For this there is clinical evidence (Lepri,1 Olson and others,2 Steffensen and others,3 Barrios and Barrière,4 Thygeson and Fritz,5 Arruga,6 Scheie and others,7 Fitzgerald and others,8 Leopold and others,9 Woods,10 and Duke-Elder11) and experimental proof (Jones and Meyer,12 Ashton, Cook, and Langham,13 Lister and Greaves,14 and Michaelson15). Provided a precise method of measuring new vascularization is used, the effect of cortisone given as drops may be compared with that of the drug injected subconjunctivally in inhibiting new-vessel formation. The method described by Campbell and Michaelson16 (1949) appears to be precise enough for the present purpose and was used References 1. Lepri, G.: Arch. ottal. 54:109, 1950. 2. Olson, J. A.; Steffensen, E. H.; Smith, R. W.; Margulis, R. R., and Whitney, E. L.: J. A. M. A. 142:1276, 1950Crossref 3. A. M. A. Arch. Ophth. 45:275, 1951. 4. Steffensen, E. H.; Wishbow, A. J.; Nagle, F. O.; Smith, R. W., and Whitney, E. L.: Am. J. Ophth. 34:345, 1951. 5. Barrios, R. R., and Barrière, R. V.: Arch. Soc. oftal. hispano-am. 11:276, 1951. 6. Thygeson, P., and Fritz, M. H.: Am. J. Ophth. 34:357, 1951. 7. Arruga, A.: Arch. Soc. oftal. hispano-am. 11:585, 1951. 8. Scheie, H. E.; Tyner, G. S.; Buesseler, J. A., and Alfano, J. E.: A. M. A. Arch. Ophth. 45:301, 1951. 9. Fitzgerald, J. R., and others: A. M. A. Arch. Ophth. 45:320, 1951.Crossref 10. Leopold, I. H.; Purnell, J. E.; Cannon, E. J.; Steinmetz, C. G., and McDonald, P. R.: Am. J. Ophth. 34:361, 1951. 11. Woods, A. C.: Am. J. Ophth. 34:945, 1951. 12. Duke-Elder, S.: Brit. J. Ophth. 35:637, 1951.Crossref 13. Jones, I. R., and Meyer, K.: Proc. Soc. Exper. Biol. 74:103, 1950.Crossref 14. Ashton, N.; Cook, C., and Langham, M.: Brit. J. Ophth. 35:718, 1951.Crossref 15. Lister, A., and Greaves, D. P.: Brit. J. Ophth. 35:725, 1951.Crossref 16. Michaelson, I. C.: A. M. A. Arch. Ophth., to be published. 17. Campbell, F. W., and Michaelson, I. C.: Brit. J. Ophth. 33:248, 1949.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png A.M.A. Archives of Ophthalmology American Medical Association

COMPARISON OF RESULTS OF CORTISONE TREATMENT BY INSTILLATION AND BY SUBCONJUNCTIVAL INJECTION: An Experimental Study

A.M.A. Archives of Ophthalmology , Volume 48 (2) – Aug 1, 1952

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Publisher
American Medical Association
Copyright
Copyright © 1952 American Medical Association. All Rights Reserved.
ISSN
0096-6339
DOI
10.1001/archopht.1952.00920010149003
Publisher site
See Article on Publisher Site

Abstract

Abstract AS TOPICAL therapy for diseases of the cornea, cortisone is frequently given, either by instillation or by subconjunctival injection. Among the effects which cortisone may have on the diseased cornea is the inhibition of new vascularization. For this there is clinical evidence (Lepri,1 Olson and others,2 Steffensen and others,3 Barrios and Barrière,4 Thygeson and Fritz,5 Arruga,6 Scheie and others,7 Fitzgerald and others,8 Leopold and others,9 Woods,10 and Duke-Elder11) and experimental proof (Jones and Meyer,12 Ashton, Cook, and Langham,13 Lister and Greaves,14 and Michaelson15). Provided a precise method of measuring new vascularization is used, the effect of cortisone given as drops may be compared with that of the drug injected subconjunctivally in inhibiting new-vessel formation. The method described by Campbell and Michaelson16 (1949) appears to be precise enough for the present purpose and was used References 1. Lepri, G.: Arch. ottal. 54:109, 1950. 2. Olson, J. A.; Steffensen, E. H.; Smith, R. W.; Margulis, R. R., and Whitney, E. L.: J. A. M. A. 142:1276, 1950Crossref 3. A. M. A. Arch. Ophth. 45:275, 1951. 4. Steffensen, E. H.; Wishbow, A. J.; Nagle, F. O.; Smith, R. W., and Whitney, E. L.: Am. J. Ophth. 34:345, 1951. 5. Barrios, R. R., and Barrière, R. V.: Arch. Soc. oftal. hispano-am. 11:276, 1951. 6. Thygeson, P., and Fritz, M. H.: Am. J. Ophth. 34:357, 1951. 7. Arruga, A.: Arch. Soc. oftal. hispano-am. 11:585, 1951. 8. Scheie, H. E.; Tyner, G. S.; Buesseler, J. A., and Alfano, J. E.: A. M. A. Arch. Ophth. 45:301, 1951. 9. Fitzgerald, J. R., and others: A. M. A. Arch. Ophth. 45:320, 1951.Crossref 10. Leopold, I. H.; Purnell, J. E.; Cannon, E. J.; Steinmetz, C. G., and McDonald, P. R.: Am. J. Ophth. 34:361, 1951. 11. Woods, A. C.: Am. J. Ophth. 34:945, 1951. 12. Duke-Elder, S.: Brit. J. Ophth. 35:637, 1951.Crossref 13. Jones, I. R., and Meyer, K.: Proc. Soc. Exper. Biol. 74:103, 1950.Crossref 14. Ashton, N.; Cook, C., and Langham, M.: Brit. J. Ophth. 35:718, 1951.Crossref 15. Lister, A., and Greaves, D. P.: Brit. J. Ophth. 35:725, 1951.Crossref 16. Michaelson, I. C.: A. M. A. Arch. Ophth., to be published. 17. Campbell, F. W., and Michaelson, I. C.: Brit. J. Ophth. 33:248, 1949.Crossref

Journal

A.M.A. Archives of OphthalmologyAmerican Medical Association

Published: Aug 1, 1952

References

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