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COMPARATIVE VALUES OF CUTANEOUS, PERCUTANEOUS AND INTRACUTANEOUS TUBERCULIN TESTS IN CHILDREN

COMPARATIVE VALUES OF CUTANEOUS, PERCUTANEOUS AND INTRACUTANEOUS TUBERCULIN TESTS IN CHILDREN The diagnostic importance of the tuberculin test is generally recognized, although the specificity of the reaction is still being discussed in the literature. There is, however, much less agreement as to the choice of the most practical method, In 1890 Koch introduced the generalized or subcutaneous tuberculin test. In 1902 Branner observed a local reaction of the skin around the site of injection of the therapeutic dose of tuberculin then in use. It was not until Pirquet discovered the exceeding sensitivity of the skin as an indicator of tuberculosis that one was able to study tuberculosis in its character of an endemic disease. A few months after Pirquet had made known his cutaneous method, efforts were made to modify it, both in the direction of increasing its sensitivity and in that of avoiding traumatism. The efforts in the first direction led to the development of the Mantoux-Mendel intracutaneous test (described http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American journal of diseases of children American Medical Association

COMPARATIVE VALUES OF CUTANEOUS, PERCUTANEOUS AND INTRACUTANEOUS TUBERCULIN TESTS IN CHILDREN

American journal of diseases of children , Volume 50 (1) – Jul 1, 1935

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Publisher
American Medical Association
Copyright
Copyright © 1935 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0096-8994
eISSN
1538-3628
DOI
10.1001/archpedi.1935.01970070113009
Publisher site
See Article on Publisher Site

Abstract

The diagnostic importance of the tuberculin test is generally recognized, although the specificity of the reaction is still being discussed in the literature. There is, however, much less agreement as to the choice of the most practical method, In 1890 Koch introduced the generalized or subcutaneous tuberculin test. In 1902 Branner observed a local reaction of the skin around the site of injection of the therapeutic dose of tuberculin then in use. It was not until Pirquet discovered the exceeding sensitivity of the skin as an indicator of tuberculosis that one was able to study tuberculosis in its character of an endemic disease. A few months after Pirquet had made known his cutaneous method, efforts were made to modify it, both in the direction of increasing its sensitivity and in that of avoiding traumatism. The efforts in the first direction led to the development of the Mantoux-Mendel intracutaneous test (described

Journal

American journal of diseases of childrenAmerican Medical Association

Published: Jul 1, 1935

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