Key PointsQuestionWhat are the clinicopathologic features of persistent chemotherapy-induced alopecia (pCIA) in breast cancer survivors? FindingsMost patients in this case series presented with either diffuse alopecia or hair thinning in the distribution of female pattern hair loss, with trichoscopic and histopathologic features indistinguishable from those of androgenetic alopecia. A few patients presented with inflammatory scarring alopecia. MeaningThis study suggests that hair follicle miniaturization (the hallmark of androgenetic alopecia) is a prominent feature in pCIA; recognized androgenetic alopecia treatments, including minoxidil and antiandrogen therapy, can also improve hair density for patients with pCIA.
JAMA Dermatology – American Medical Association
Published: Nov 29, 2021