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Clinical Trial Registration

Clinical Trial Registration Editorials represent the opinions EDITORIALS of the authors and THE JOURNAL and not those of the American Medical Association. A Statement From the International Committee of Medical Journal Editors Irrespective of their scientific interest, trial results that place Catherine D. DeAngelis, MD, MPH financial interests at risk are particularly likely to remain Jeffrey M. Drazen, MD unpublished and hidden from public view. The interests of Frank A. Frizelle, MBChB, MMedSc, FRACS the sponsor or authors notwithstanding, anyone should be able to learn of any trial’s existence and its important char- Charlotte Haug, MD, PhD, MSc acteristics. John Hoey, MD The case against selective reporting is particularly com- Richard Horton, FRCP pelling for research that tests interventions that could en- ter mainstream clinical practice. Rather than a single trial, Sheldon Kotzin, MLS it is usually a body of evidence, consisting of many studies, Christine Laine, MD, MPH that changes medical practice. When research sponsors or Ana Marusic, MD, PhD investigators conceal the presence of selected trials, these A. John P. M. Overbeke, MD, PhD studies cannot influence the thinking of patients, clini- cians, other researchers, and experts who write practice Torben V. Schroeder, MD, DMSc guidelines or decide on insurance-coverage http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

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Publisher
American Medical Association
Copyright
Copyright 2004 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.292.11.1363
pmid
15355936
Publisher site
See Article on Publisher Site

Abstract

Editorials represent the opinions EDITORIALS of the authors and THE JOURNAL and not those of the American Medical Association. A Statement From the International Committee of Medical Journal Editors Irrespective of their scientific interest, trial results that place Catherine D. DeAngelis, MD, MPH financial interests at risk are particularly likely to remain Jeffrey M. Drazen, MD unpublished and hidden from public view. The interests of Frank A. Frizelle, MBChB, MMedSc, FRACS the sponsor or authors notwithstanding, anyone should be able to learn of any trial’s existence and its important char- Charlotte Haug, MD, PhD, MSc acteristics. John Hoey, MD The case against selective reporting is particularly com- Richard Horton, FRCP pelling for research that tests interventions that could en- ter mainstream clinical practice. Rather than a single trial, Sheldon Kotzin, MLS it is usually a body of evidence, consisting of many studies, Christine Laine, MD, MPH that changes medical practice. When research sponsors or Ana Marusic, MD, PhD investigators conceal the presence of selected trials, these A. John P. M. Overbeke, MD, PhD studies cannot influence the thinking of patients, clini- cians, other researchers, and experts who write practice Torben V. Schroeder, MD, DMSc guidelines or decide on insurance-coverage

Journal

JAMAAmerican Medical Association

Published: Sep 15, 2004

References