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- Publisher
- American Medical Association
- Copyright
- Copyright © 1961 American Medical Association. All Rights Reserved.
- ISSN
- 0003-987X
- eISSN
- 1538-3652
- DOI
- 10.1001/archderm.1961.01580170066009
- Publisher site
- See Article on Publisher Site
Abstract
Abstract The relationships between hair loss, hair growth, and vascular supply in the human scalp have not been precisely delineated. Alopecias from severe inflammatory processes which destroy the follicular unit have been fully documented. The combination of genetic susceptibility and androgenic inhibition of follicular growth in male and female patterned baldness is well recognized, but the role played by the vascular system is unknown. Little is understood concerning the pathogenesis of the mildly inflammatory alopecias, exemplified by alopecia areata, alopecia totalis, and pseudopelade of Brocq. Chronic diffuse thinning of the hair in women in the absence of known hereditary factors, while apparently becoming increasingly common, has not been satisfactorily explained. In a recent study, Kligman1 has shown that temporary thinning of scalp hair following severe fevers, infections, pregnancy, and heparin administration is due to accelerated production of normal telogen hairs. The causative mechanisms in this group likewise remain obscure. This References 1. Kligman, A.: Pathologic Dynamics of Human Hair Loss , Arch. Derm. 83:175, 1961.Crossref 2. Gomori, G.: Microscopic Histochemistry: Principles and Practice , Chicago, The University of Chicago Press, 1952. 3. Spalteholz, W., in Handbuch der Haut und Geschlechtskrankheiten , edited by J. Jadassohn, Vol. 1, Berlin, Springer-Verlag, 1927, pp. 379-433 4. Durward, A., and Rudall, K.: The Vascularity and Patterns of Growth of Hair Follicles , in The Biology of Hair Growth , New York, Academic Press, Inc., 1958, p. 189. 5. Ellis, R.: Ageing in the Human Scalp , in The Biology of Hair Growth , New York, Academic Press, Inc., 1958, p. 469. 6. Montagna, W., and Ellis, R.: The Vascularity and Innervation of Human Hair Follicles , in The Biology of Hair Growth , New York, Academic Press, Inc., 1958, p. 219. 7. Montagna, W., Editor: The Biology of Hair Growth , New York, Academic Press, Inc., 1958, p. 500. 8. Ellis, R., and Moretti, G.: Vascular Patterns Associated with Catagen Hair Follicles in the Human Scalp , Ann. N.Y. Acad. Sci. 83:448, 1959.Crossref 9. Kopf, A., and Orentreich, N.: Alkaline Phosphatase in Alopecia Areata , A.M.A. Arch. Derm. 76:288, 1957.Crossref 10. Bannon, E.: Mechanisms of Carbohydrate Metabolism , Advance Enzymol. 3:149, 1943. 11. Ely, J., and Rose, M.: Effect of Protein Free Diet on the Alkaline and Acid Phosphatase Activity of the Liver of the Rat , Nature 168:323, 1951.Crossref 12. Flock, E., and Ballman, V.: Alkaline Phosphatase in the Intestinal Lymph of the Rat , J. Biol. Chem. 175:439, 1948. 13. Moog, F.: The Physiological Significance of the Phosphomonoesterases , Biol. Rev. 21:41, 1946.Crossref 14. Abel, R., and Lewis, G.: Postoperative (Pressure) Alopecia , Arch. Derm. 81:34, 1960.Crossref
Journal
Archives of Dermatology – American Medical Association
Published: Nov 1, 1961
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