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CHROMATOPHORE (MYO-EPITHELIAL) TUMORS OF THE MAMMARY GLAND

CHROMATOPHORE (MYO-EPITHELIAL) TUMORS OF THE MAMMARY GLAND Abstract For more than twenty years I have been acutely sensible of the fact that certain globular cancers of the breast present a particularly bad prognosis. In addition to their external form, they present a varied histologic structure which requires the assumption of a wide latitude of cell metaplasia to keep them within the group of epithelial tumors. Recently I encountered a patient whose tumor seemed to be a connecting link between the aforementioned group and the intracanalicular fibro-adenomas. As the cells of this tumor seemed to spring from its subepithelial cells, I am calling growths of this type chromatophore tumors, realizing that this is little more than a symbol. Since they do not produce pigment, one cannot call them melanomas, though they duplicate the histologic structure of the pigmented tumors in a striking manner. Amelanotic melanomas would be a more accurate though cumbersome designation. The use of a term suggesting References 1. This judgment is based on previous studies made on chromomas : Ann. Surg. 60:89 ( (July) ) 1914 2. 87:99 (Jan.) 1928 3. Surgical Pathology of the Skin , Philadelphia, J. B. Lippincott Company, 1931, p. 145 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Surgery American Medical Association

CHROMATOPHORE (MYO-EPITHELIAL) TUMORS OF THE MAMMARY GLAND

Archives of Surgery , Volume 28 (2) – Feb 1, 1934

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Publisher
American Medical Association
Copyright
Copyright © 1934 American Medical Association. All Rights Reserved.
ISSN
0004-0010
eISSN
1538-3644
DOI
10.1001/archsurg.1934.01170140087005
Publisher site
See Article on Publisher Site

Abstract

Abstract For more than twenty years I have been acutely sensible of the fact that certain globular cancers of the breast present a particularly bad prognosis. In addition to their external form, they present a varied histologic structure which requires the assumption of a wide latitude of cell metaplasia to keep them within the group of epithelial tumors. Recently I encountered a patient whose tumor seemed to be a connecting link between the aforementioned group and the intracanalicular fibro-adenomas. As the cells of this tumor seemed to spring from its subepithelial cells, I am calling growths of this type chromatophore tumors, realizing that this is little more than a symbol. Since they do not produce pigment, one cannot call them melanomas, though they duplicate the histologic structure of the pigmented tumors in a striking manner. Amelanotic melanomas would be a more accurate though cumbersome designation. The use of a term suggesting References 1. This judgment is based on previous studies made on chromomas : Ann. Surg. 60:89 ( (July) ) 1914 2. 87:99 (Jan.) 1928 3. Surgical Pathology of the Skin , Philadelphia, J. B. Lippincott Company, 1931, p. 145

Journal

Archives of SurgeryAmerican Medical Association

Published: Feb 1, 1934

References