Chlorthalidone-Induced Hypercalcemia
Abstract
To the Editor.—
In the July 15 issue of The Journal (229:267, 1974), Palmer described a patient with hypercalcemia, presumedly secondary to chlorthalidone (Hygroton) administration. Previous reports have shown that thiazides and chlorthalidone can cause permanent hypercalcemia in patients with hyperparathyroidism.1,2 Adams et al3 suggested a provocative test with thiazides for the diagnosis of hyperparathyroidism in patients suffering from nephrolithiasis and hypercalciuria.
Since the...