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Chloroquine Retinopathy: Evaluation by Fluorescein Fundus Angiography

Chloroquine Retinopathy: Evaluation by Fluorescein Fundus Angiography Abstract The maculas of patients with chloroquine retinopathy exhibit a dramatic fluorescence when studied by intravenous fluorescein angiography. This fluorescence is interpreted as being due to a dysplasia of the macular pigment epithelium, which allows the underlying choroidal fluorescence to show through. We think that fluorescein fundus angiography is a new and valuable adjunct in the diagnosis and evaluation of chloroquine retinopathy. References 1. Novotny, H.R., and Alvis, D.L.: A Method of Photographing Fluorescence in Circulating Blood in the Human Retina , Circulation 24:82-86 ( (July) ) 1961.Crossref 2. Norton, E.W.D.: " Angiography of the Ocular Fundus ," in Smith, J. L. (ed.): Miami Neuro-ophthalmology Symposium , St. Louis: C. V. Mosby Co., 1965, vol 2, pp 62-81. 3. Norton, E.W.D., et al: Fluorescein Fundus Photography: An Aid in the Differential Diagnosis of Posterior Ocular Lesions , Trans Amer Acad Ophthal Otolaryng 68:755-765 ( (Sept-Oct) ) 1964. 4. Smith, J.L.; Gass, J.D.M.; and Justice, J., Jr.: Fluorescein Fundus Photography of Angioid Streaks , Brit J Ophthal 48:517-521 ( (Oct) ) 1964.Crossref 5. Dollery, C.T., and Oakley, N.W.: Reversal of Retinal Vascular Changes in Diabetes , Diabetes 14: 121-127 ( (March) ) 1965. 6. Norton, E.W.D., and Gutman, F.: Diabetic Retinopathy Studied by Fluorescein Angiography , Ophthalmologica 150:5-17, 1965.Crossref 7. Miller, S.J.H.; Sanders, M.D.; and Ffytche, T.J.: Fluorescein Fundus Photography in the Detection of Early Papilledema and Its Differentiation From Pseudo-papilledema , Lancet 2:651-654 ( (Oct 2) ) 1965.Crossref 8. Norton, E.W.D., et al: Fluorescein in the Study of Macular Disease , Trans Amer Acad Ophthal Otolaryng 69:631-642 ( (July-Aug) ) 1965. 9. Justice, J., Jr., and Sever, R.J.: " Technique of Fluorescein Fundus Photography ," in Smith, J. L. (ed.): Miami Neuro-ophthalmology Symposium , St. Louis: C. V. Mosby Co., 1965, vol 2, pp 82-83. 10. Ferrer, O.M.: Serial Fluorescein Fundus Photography of Retinal Circulation: A Description of Technique , Amer J Ophthal 60:587-591 ( (Oct) ) 1965. 11. Wetterholm, D.H., and Winter, F.C.: Histopathology of Chloroquine Retinal Toxicity , Arch Ophthal 71:82-87 ( (Jan) ) 1964.Crossref 12. Goldman, L., and Preston, R.H.: Reactions to Chloroquine Observed During the Treatment of Various Dermatologic Disorders , Amer J Trop Med 6:654-657, 1957. 13. Bernstein, H.N., and Ginsberg, J.: The Pathology of Chloroquine Retinopathy , Arch Ophthal 71:238-245 ( (Feb) ) 1964.Crossref 14. Meier-Ruge, W.: Experimental Investigation of the Morphogenesis of Chloroquine Retinopathy , Arch Ophthal 73:540-544 ( (April) ) 1965.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Ophthalmology American Medical Association

Chloroquine Retinopathy: Evaluation by Fluorescein Fundus Angiography

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Publisher
American Medical Association
Copyright
Copyright © 1966 American Medical Association. All Rights Reserved.
ISSN
0003-9950
eISSN
1538-3687
DOI
10.1001/archopht.1966.03850010380016
Publisher site
See Article on Publisher Site

Abstract

Abstract The maculas of patients with chloroquine retinopathy exhibit a dramatic fluorescence when studied by intravenous fluorescein angiography. This fluorescence is interpreted as being due to a dysplasia of the macular pigment epithelium, which allows the underlying choroidal fluorescence to show through. We think that fluorescein fundus angiography is a new and valuable adjunct in the diagnosis and evaluation of chloroquine retinopathy. References 1. Novotny, H.R., and Alvis, D.L.: A Method of Photographing Fluorescence in Circulating Blood in the Human Retina , Circulation 24:82-86 ( (July) ) 1961.Crossref 2. Norton, E.W.D.: " Angiography of the Ocular Fundus ," in Smith, J. L. (ed.): Miami Neuro-ophthalmology Symposium , St. Louis: C. V. Mosby Co., 1965, vol 2, pp 62-81. 3. Norton, E.W.D., et al: Fluorescein Fundus Photography: An Aid in the Differential Diagnosis of Posterior Ocular Lesions , Trans Amer Acad Ophthal Otolaryng 68:755-765 ( (Sept-Oct) ) 1964. 4. Smith, J.L.; Gass, J.D.M.; and Justice, J., Jr.: Fluorescein Fundus Photography of Angioid Streaks , Brit J Ophthal 48:517-521 ( (Oct) ) 1964.Crossref 5. Dollery, C.T., and Oakley, N.W.: Reversal of Retinal Vascular Changes in Diabetes , Diabetes 14: 121-127 ( (March) ) 1965. 6. Norton, E.W.D., and Gutman, F.: Diabetic Retinopathy Studied by Fluorescein Angiography , Ophthalmologica 150:5-17, 1965.Crossref 7. Miller, S.J.H.; Sanders, M.D.; and Ffytche, T.J.: Fluorescein Fundus Photography in the Detection of Early Papilledema and Its Differentiation From Pseudo-papilledema , Lancet 2:651-654 ( (Oct 2) ) 1965.Crossref 8. Norton, E.W.D., et al: Fluorescein in the Study of Macular Disease , Trans Amer Acad Ophthal Otolaryng 69:631-642 ( (July-Aug) ) 1965. 9. Justice, J., Jr., and Sever, R.J.: " Technique of Fluorescein Fundus Photography ," in Smith, J. L. (ed.): Miami Neuro-ophthalmology Symposium , St. Louis: C. V. Mosby Co., 1965, vol 2, pp 82-83. 10. Ferrer, O.M.: Serial Fluorescein Fundus Photography of Retinal Circulation: A Description of Technique , Amer J Ophthal 60:587-591 ( (Oct) ) 1965. 11. Wetterholm, D.H., and Winter, F.C.: Histopathology of Chloroquine Retinal Toxicity , Arch Ophthal 71:82-87 ( (Jan) ) 1964.Crossref 12. Goldman, L., and Preston, R.H.: Reactions to Chloroquine Observed During the Treatment of Various Dermatologic Disorders , Amer J Trop Med 6:654-657, 1957. 13. Bernstein, H.N., and Ginsberg, J.: The Pathology of Chloroquine Retinopathy , Arch Ophthal 71:238-245 ( (Feb) ) 1964.Crossref 14. Meier-Ruge, W.: Experimental Investigation of the Morphogenesis of Chloroquine Retinopathy , Arch Ophthal 73:540-544 ( (April) ) 1965.Crossref

Journal

Archives of OphthalmologyAmerican Medical Association

Published: Sep 1, 1966

References

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