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Childhood Bullous Pemphigoid

Childhood Bullous Pemphigoid Abstract To the Editor.— We enjoyed the comprehensive review on childhood bullous pemphigoid (BP) by Nemeth et al1 in the March 1991 issue of the Archives, and we would like to draw the authors' attention to one additional case they did not mention2,3 that we think is of interest. A 3-month-old boy had lesions localized to his feet; this, indeed, appears to be a striking clinical feature of BP at this age. The bullous eruption dramatically responded to sulfapyridine therapy (120 mg/d) for 6 weeks. No recurrence has been seen after 3 years of follow-up. The mother has had, during pregnancy, an eruption thought to be the "pruritic urticarial papules and plaques of pregnancy," but, for the reasons discussed elsewhere,3 we could not exclude herpes gestationis; no circulating antibodies in the mother's serum were detectable by Western blotting 3 months after delivery.2 Therefore, we could not establish References 1. Nemeth AJ, Klein AD, Gould EW, Schachner LA. Childhood bullous pemphigoid . Arch Dermatol. 1991;127:378-386.Crossref 2. Abba Z, Harms M, Didierjean L, Saurat JH. Pemphigoïde bulleuse chez un enfant de 3 mois . Ann Dermatol Venereol. 1988;115:1138-1139. 3. Saurat JH. Immunofluorescence biopsy for pruritic urticarial papules and plaques of pregnancy . J Am Acad Dermatol. 1989;20:711.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

Childhood Bullous Pemphigoid

Archives of Dermatology , Volume 127 (10) – Oct 1, 1991

Childhood Bullous Pemphigoid

Abstract

Abstract To the Editor.— We enjoyed the comprehensive review on childhood bullous pemphigoid (BP) by Nemeth et al1 in the March 1991 issue of the Archives, and we would like to draw the authors' attention to one additional case they did not mention2,3 that we think is of interest. A 3-month-old boy had lesions localized to his feet; this, indeed, appears to be a striking clinical feature of BP at this age. The bullous eruption dramatically responded to sulfapyridine therapy (120...
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Publisher
American Medical Association
Copyright
Copyright © 1991 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1991.01680090152025
Publisher site
See Article on Publisher Site

Abstract

Abstract To the Editor.— We enjoyed the comprehensive review on childhood bullous pemphigoid (BP) by Nemeth et al1 in the March 1991 issue of the Archives, and we would like to draw the authors' attention to one additional case they did not mention2,3 that we think is of interest. A 3-month-old boy had lesions localized to his feet; this, indeed, appears to be a striking clinical feature of BP at this age. The bullous eruption dramatically responded to sulfapyridine therapy (120 mg/d) for 6 weeks. No recurrence has been seen after 3 years of follow-up. The mother has had, during pregnancy, an eruption thought to be the "pruritic urticarial papules and plaques of pregnancy," but, for the reasons discussed elsewhere,3 we could not exclude herpes gestationis; no circulating antibodies in the mother's serum were detectable by Western blotting 3 months after delivery.2 Therefore, we could not establish References 1. Nemeth AJ, Klein AD, Gould EW, Schachner LA. Childhood bullous pemphigoid . Arch Dermatol. 1991;127:378-386.Crossref 2. Abba Z, Harms M, Didierjean L, Saurat JH. Pemphigoïde bulleuse chez un enfant de 3 mois . Ann Dermatol Venereol. 1988;115:1138-1139. 3. Saurat JH. Immunofluorescence biopsy for pruritic urticarial papules and plaques of pregnancy . J Am Acad Dermatol. 1989;20:711.Crossref

Journal

Archives of DermatologyAmerican Medical Association

Published: Oct 1, 1991

References