Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

CHICAGO DERMATOLOGICAL SOCIETY

CHICAGO DERMATOLOGICAL SOCIETY Abstract Reactive Perforating Collagenosis. Presented by David F. Fretzin, MD A 24-year-old married woman has a history of persistent scattered lesions since the age of 5 years. They occur following minor trauma, especially insect bites, and develop from a small papule to variably sized, crusted, and occasionally exudative nodules. There is minor pain with the onset of the lesion and some pruritus subsequently. Individual lesions heal slowly during several months, frequently leaving a small scar or leukodermic patch (Fig 1). There was no family history of skin disease.A section of a nodule from her forearm shows a centrally ulcerated, crusted lesion with pseudoepitheliomatous hyperplasia of the adjacent epidermis. The crusted portion contains necrotic debris consisting of neutrophils and refractile collagen bundles. Narrow collagen bundles perforate the adjacent epithelium into the central crust. Variable degrees of necrobiosis, chronic inflammation, and reactive granulation tissue are present beneath the central ulcer! Stains for elastic fibers in the debris are negative References 1. Weiner J: Kyrles disease: Hyperkeratosis follicularis et parafollicularis in cutem penetrans in siblings . Arch Dermatol 95:329-332, 1967.Crossref 2. Mehregan AH: Reactive perforating collagenosis . Arch Dermatol 96:277-282, 1967.Crossref 3. Bovenmeyer DA: Reactive perforating collagenosis . Arch Dermatol 102:313-317, 1970.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

CHICAGO DERMATOLOGICAL SOCIETY

Archives of Dermatology , Volume 109 (5) – May 1, 1974

Loading next page...
 
/lp/american-medical-association/chicago-dermatological-society-py0tFnHUvQ
Publisher
American Medical Association
Copyright
Copyright © 1974 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1974.01630050076036
Publisher site
See Article on Publisher Site

Abstract

Abstract Reactive Perforating Collagenosis. Presented by David F. Fretzin, MD A 24-year-old married woman has a history of persistent scattered lesions since the age of 5 years. They occur following minor trauma, especially insect bites, and develop from a small papule to variably sized, crusted, and occasionally exudative nodules. There is minor pain with the onset of the lesion and some pruritus subsequently. Individual lesions heal slowly during several months, frequently leaving a small scar or leukodermic patch (Fig 1). There was no family history of skin disease.A section of a nodule from her forearm shows a centrally ulcerated, crusted lesion with pseudoepitheliomatous hyperplasia of the adjacent epidermis. The crusted portion contains necrotic debris consisting of neutrophils and refractile collagen bundles. Narrow collagen bundles perforate the adjacent epithelium into the central crust. Variable degrees of necrobiosis, chronic inflammation, and reactive granulation tissue are present beneath the central ulcer! Stains for elastic fibers in the debris are negative References 1. Weiner J: Kyrles disease: Hyperkeratosis follicularis et parafollicularis in cutem penetrans in siblings . Arch Dermatol 95:329-332, 1967.Crossref 2. Mehregan AH: Reactive perforating collagenosis . Arch Dermatol 96:277-282, 1967.Crossref 3. Bovenmeyer DA: Reactive perforating collagenosis . Arch Dermatol 102:313-317, 1970.Crossref

Journal

Archives of DermatologyAmerican Medical Association

Published: May 1, 1974

References