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CHEMOTHERAPY OF PRIMARY ATYPICAL PNEUMONIA

CHEMOTHERAPY OF PRIMARY ATYPICAL PNEUMONIA Soon after chlortetracycline (Aureomycin) became available for clinical evaluation, several reports presented data showing that this drug is effective in primary atypical pneumonia.1 The paper by one of us (G. M.) and Shragg1d reported that a sharp difference was noted between the duration of elevation of temperature in a group of patients treated with chlortetracycline and in a comparable group treated with penicillin. Since that time we have had additional opportunity to use chlortetracycline in this disease and have consistently observed a prompt drop in temperature and rapid clinical recovery. Experience with chloramphenicol (Chloromycetin) and oxytetracycline (Terramycin) has been more limited, but results have been generally similar. Partly because adequately controlled studies have been so few in number and partly because primary atypical pneumonia is a disease that is often of short duration even when no chemotherapy is used, there has been considerable reluctance in some quarters to http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

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References (6)

Publisher
American Medical Association
Copyright
Copyright © 1954 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.1954.02940410009003
Publisher site
See Article on Publisher Site

Abstract

Soon after chlortetracycline (Aureomycin) became available for clinical evaluation, several reports presented data showing that this drug is effective in primary atypical pneumonia.1 The paper by one of us (G. M.) and Shragg1d reported that a sharp difference was noted between the duration of elevation of temperature in a group of patients treated with chlortetracycline and in a comparable group treated with penicillin. Since that time we have had additional opportunity to use chlortetracycline in this disease and have consistently observed a prompt drop in temperature and rapid clinical recovery. Experience with chloramphenicol (Chloromycetin) and oxytetracycline (Terramycin) has been more limited, but results have been generally similar. Partly because adequately controlled studies have been so few in number and partly because primary atypical pneumonia is a disease that is often of short duration even when no chemotherapy is used, there has been considerable reluctance in some quarters to

Journal

JAMAAmerican Medical Association

Published: Feb 13, 1954

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