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Cheilitis Granulomatosa and Melkersson-Rosenthal Syndrome

Cheilitis Granulomatosa and Melkersson-Rosenthal Syndrome Abstract Diseases which are more or less confined to specific anatomic locations are of special interest. This is particularly true of disorders of the lips because of the possibility of subsequent malignant change. A number of cheilitides have been welldocumented for many years, but in most cases the etiology is obscure. Actinic cheilitis is a notable exception to the rule. Cheilitis exfoliativa, cheilitis glandularis, and cheilitis glandularis apostematosa are diseases in which the mucous membranes and the associated mucous glands are involved. Sometimes secondary changes, such as lymph stasis and sclerosis, cause hypertrophy. Enlargement of the lips is known as macrocheilia and may be due to various inflammatory or neoplastic processes including hemangioma, lymphangioma, hypertrophy of the labial salivary glands, and recurrent attacks of cellulitis or angioneurotic edema. Miescher,11 in 1945, reported 6 cases in which the onset was sudden and the course progressive, terminating in chronic enlargement of the References 1. This case report is presented through the courtesy of Dr. Henry Michelson and Dr. Sheldon Mandel. 2. Conway, H.: Macrocheilia Due to Hyperplasia of the Labial Salivary Glands: Operative Correction , Surg., Gynec. & Obst. 66:1024-1031 ( (June) ) 1938. 3. Doepfmer, R.: Bildberichte: Glossitis granulomatosa und gleichzeitiger Laryngitis Granulomatosa , Hautarzt 11:40 ( (Jan.) ) 1960. 4. Gahlen, W., and Brückner, B.: Beitrag zur Pathogenese des Melkersson-Rosenthal-Syndromes , Arch. Dermat. u. Syph. 192:468-477 ( (April) ) 1951. 5. Gromzig, H., and Kuniss, G.: Beitrag zur Klinik der Essentiellen granulömatosen Macrocheilie , Z. Haut-u. Geschl.-Kr. , 15:9-13 ( (July) ) 1953. 6. Hornstein, O.: Beteiligung des lymphatischen Systems am Komplex der "Cheilitis" ("Pareiitis" etc.) granulomatosa , Arch. Dermat. u. Syph. 198: 396-416 ( (Aug.) ) 1954. 7. Kirch, W. A., and New, G. B.: Permanent Enlargement of the Lips and Face , J.A.M.A. 100: 1230-1232 ( (April) ) 1933. 8. Klaus, S., and Brunsting, L.: Melkersson's Syndrome (Persistent Swelling of the Face, Facial Paralysis and Lingua Plicata): Report of Case , Proc. Staff Meet. Mayo Clin. 34:365-370 ( (July 22) ) 1933. 9. Laymon, C. W., and Hill, E. M.: An Appraisal of Hyalinosis Cutis et Mucosae , A.M.A. Arch. Dermat. 75:55-65 ( (Jan.) ) 1957. 10. Melkersson, E.: Ett fall av recidiverande facialispares i samband med angioneurotiskt ödem , Hygiea 90:737-741, 1928. 11. Miescher, G.: Cheilitis et Pareitis granulomatosa ohne Facialisparese bei Vorhandensein einer Lingua scrotalis , Dermatologica 112:536-537, 1956. 12. Miescher, G.: Über Essentielle granulomatöse Makrocheilie (Cheilitis granulomatosa) , Dermatologica 91:57-85, 1945. 13. Richter, R., and Johne, H. O.: Über Beziehungen des Melkersson-Rosenthal-Syndrom zur Cheilitis granulomatosa (Miescher) , Arch. Dermat. u. Syph. 190:486-492 ( (July) ) 1950. 14. Rosenthal, C.: Klinisch-erbbiologischer Beitrag zur Konstitutions-Pathologie: Geminsames Aufreten von (rezidivierender familiarer) Facialislahmung, Angioneuroticischem Gesichtsödem and Lingua plicata in Arthritismus-Familien , Ztschr. ges. Neurol. Psychiat. 131:475-501, 1930. 15. Schuermann, H.: Glossitis und Pareiitis granulomatosa , Hautarzt 3:538-542 ( (Dec.) ) 1952. 16. Stumpf, W., and Schuppener, H. J.: Das Melkersson-Rosenthal Syndrom: Untersuchungen zur Psychchogenese , Klin. Wchnschr. 35:882-886 ( (Sept.) ) 1957. 17. Touraine and Solente: Cheilite glandulaire (maladie de Volkmann-Baelz) (Adénomes de la lèvre inférieure. Etat pré-cancerux) , Bull. Soc. franç. de dermat. et syph. 40:89-92 ( (Jan.) ) 1933. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

Cheilitis Granulomatosa and Melkersson-Rosenthal Syndrome

Archives of Dermatology , Volume 83 (1) – Jan 1, 1961

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Publisher
American Medical Association
Copyright
Copyright © 1961 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1961.01580070118013
Publisher site
See Article on Publisher Site

Abstract

Abstract Diseases which are more or less confined to specific anatomic locations are of special interest. This is particularly true of disorders of the lips because of the possibility of subsequent malignant change. A number of cheilitides have been welldocumented for many years, but in most cases the etiology is obscure. Actinic cheilitis is a notable exception to the rule. Cheilitis exfoliativa, cheilitis glandularis, and cheilitis glandularis apostematosa are diseases in which the mucous membranes and the associated mucous glands are involved. Sometimes secondary changes, such as lymph stasis and sclerosis, cause hypertrophy. Enlargement of the lips is known as macrocheilia and may be due to various inflammatory or neoplastic processes including hemangioma, lymphangioma, hypertrophy of the labial salivary glands, and recurrent attacks of cellulitis or angioneurotic edema. Miescher,11 in 1945, reported 6 cases in which the onset was sudden and the course progressive, terminating in chronic enlargement of the References 1. This case report is presented through the courtesy of Dr. Henry Michelson and Dr. Sheldon Mandel. 2. Conway, H.: Macrocheilia Due to Hyperplasia of the Labial Salivary Glands: Operative Correction , Surg., Gynec. & Obst. 66:1024-1031 ( (June) ) 1938. 3. Doepfmer, R.: Bildberichte: Glossitis granulomatosa und gleichzeitiger Laryngitis Granulomatosa , Hautarzt 11:40 ( (Jan.) ) 1960. 4. Gahlen, W., and Brückner, B.: Beitrag zur Pathogenese des Melkersson-Rosenthal-Syndromes , Arch. Dermat. u. Syph. 192:468-477 ( (April) ) 1951. 5. Gromzig, H., and Kuniss, G.: Beitrag zur Klinik der Essentiellen granulömatosen Macrocheilie , Z. Haut-u. Geschl.-Kr. , 15:9-13 ( (July) ) 1953. 6. Hornstein, O.: Beteiligung des lymphatischen Systems am Komplex der "Cheilitis" ("Pareiitis" etc.) granulomatosa , Arch. Dermat. u. Syph. 198: 396-416 ( (Aug.) ) 1954. 7. Kirch, W. A., and New, G. B.: Permanent Enlargement of the Lips and Face , J.A.M.A. 100: 1230-1232 ( (April) ) 1933. 8. Klaus, S., and Brunsting, L.: Melkersson's Syndrome (Persistent Swelling of the Face, Facial Paralysis and Lingua Plicata): Report of Case , Proc. Staff Meet. Mayo Clin. 34:365-370 ( (July 22) ) 1933. 9. Laymon, C. W., and Hill, E. M.: An Appraisal of Hyalinosis Cutis et Mucosae , A.M.A. Arch. Dermat. 75:55-65 ( (Jan.) ) 1957. 10. Melkersson, E.: Ett fall av recidiverande facialispares i samband med angioneurotiskt ödem , Hygiea 90:737-741, 1928. 11. Miescher, G.: Cheilitis et Pareitis granulomatosa ohne Facialisparese bei Vorhandensein einer Lingua scrotalis , Dermatologica 112:536-537, 1956. 12. Miescher, G.: Über Essentielle granulomatöse Makrocheilie (Cheilitis granulomatosa) , Dermatologica 91:57-85, 1945. 13. Richter, R., and Johne, H. O.: Über Beziehungen des Melkersson-Rosenthal-Syndrom zur Cheilitis granulomatosa (Miescher) , Arch. Dermat. u. Syph. 190:486-492 ( (July) ) 1950. 14. Rosenthal, C.: Klinisch-erbbiologischer Beitrag zur Konstitutions-Pathologie: Geminsames Aufreten von (rezidivierender familiarer) Facialislahmung, Angioneuroticischem Gesichtsödem and Lingua plicata in Arthritismus-Familien , Ztschr. ges. Neurol. Psychiat. 131:475-501, 1930. 15. Schuermann, H.: Glossitis und Pareiitis granulomatosa , Hautarzt 3:538-542 ( (Dec.) ) 1952. 16. Stumpf, W., and Schuppener, H. J.: Das Melkersson-Rosenthal Syndrom: Untersuchungen zur Psychchogenese , Klin. Wchnschr. 35:882-886 ( (Sept.) ) 1957. 17. Touraine and Solente: Cheilite glandulaire (maladie de Volkmann-Baelz) (Adénomes de la lèvre inférieure. Etat pré-cancerux) , Bull. Soc. franç. de dermat. et syph. 40:89-92 ( (Jan.) ) 1933.

Journal

Archives of DermatologyAmerican Medical Association

Published: Jan 1, 1961

References