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CHANGING TRENDS IN CLINICAL INVESTIGATION

CHANGING TRENDS IN CLINICAL INVESTIGATION Abstract Changing trends in American medicine, medical education, and research have for many years been favorite subjects for messages from chairmen. Nevertheless, since this represents the Centennial Meeting of the Section on Experimental Medicine and Therapeutics, it seems timely to discuss briefly a few of the problems related to the dynamic developments in science in terms of their impact on clinical investigation. The word "clinical" is derived from the Greek word klinikos which means bed; hence, Dr. Fuller Albright pointed out 15 years ago: "Since animals do not sleep in beds, it is quite clear that 'clinical investigation' has primarily to do with the investigation of sick people and is concerned only secondarily, if at all, with sick laboratory animals."1 One could argue the restrictions imposed by the above statement. Few would disagree that the greatest contributions from clinical investigation have come from success in opening up new knowledge of References 1. Albright, F.: Presidential Address: Some of "Do's" and "Do-Not's" in Clinical Investigation , J. Clin. Invest. 23:921-926 ( (Nov.) ) 1944.Crossref 2. Beecher, H. K.: Experimentation in Man , J. A. M. A. 169:461-478 ( (Jan.) ) 1959.Crossref 3. Oliver, J., and others: Renal Lesions of Electrolyte Imbalance: I. Structural Alterations in Potassium-Depleted Rats , J. Exper. Med. 106:563-574 ( (Oct.) ) 1957.Crossref 4. Hollander, W., Jr., and others: Defect in Renal Tubular Reabsorption of Water Associated with Potassium Depletion in Rats , Am. J. Physiol. 189:557-563 ( (June) ) 1957. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

CHANGING TRENDS IN CLINICAL INVESTIGATION

JAMA , Volume 171 (15) – Dec 12, 1959

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Publisher
American Medical Association
Copyright
Copyright © 1959 American Medical Association. All Rights Reserved.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.1959.03010330005002
Publisher site
See Article on Publisher Site

Abstract

Abstract Changing trends in American medicine, medical education, and research have for many years been favorite subjects for messages from chairmen. Nevertheless, since this represents the Centennial Meeting of the Section on Experimental Medicine and Therapeutics, it seems timely to discuss briefly a few of the problems related to the dynamic developments in science in terms of their impact on clinical investigation. The word "clinical" is derived from the Greek word klinikos which means bed; hence, Dr. Fuller Albright pointed out 15 years ago: "Since animals do not sleep in beds, it is quite clear that 'clinical investigation' has primarily to do with the investigation of sick people and is concerned only secondarily, if at all, with sick laboratory animals."1 One could argue the restrictions imposed by the above statement. Few would disagree that the greatest contributions from clinical investigation have come from success in opening up new knowledge of References 1. Albright, F.: Presidential Address: Some of "Do's" and "Do-Not's" in Clinical Investigation , J. Clin. Invest. 23:921-926 ( (Nov.) ) 1944.Crossref 2. Beecher, H. K.: Experimentation in Man , J. A. M. A. 169:461-478 ( (Jan.) ) 1959.Crossref 3. Oliver, J., and others: Renal Lesions of Electrolyte Imbalance: I. Structural Alterations in Potassium-Depleted Rats , J. Exper. Med. 106:563-574 ( (Oct.) ) 1957.Crossref 4. Hollander, W., Jr., and others: Defect in Renal Tubular Reabsorption of Water Associated with Potassium Depletion in Rats , Am. J. Physiol. 189:557-563 ( (June) ) 1957.

Journal

JAMAAmerican Medical Association

Published: Dec 12, 1959

References