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Changes in Kayser-Fleischer Ring During Treatment of Hepatolenticular Degeneration

Changes in Kayser-Fleischer Ring During Treatment of Hepatolenticular Degeneration Abstract Kayser-Fleischer rings were observed in two patients over a three-year period during treatment of hepatolenticular degeneration (Wilson's disease). The clinical improvement of these patients did not correlate with changes in the corneal deposits. The neuropathologic implications of these observations are discussed. References 1. Bonamour, G., and Leopold: Le cercle vert de la cornée et la semble-cataract en fleur de tournesol dans la maladie de Wilson , Bull Soc Ophtal Lyon 7:411-414 ( (July-Aug) ) 1960. 2. Boudin, G., et al: Notre expérience du traitment de la maladie de Wilson par le penicillamine , Rev Neurolog 109:82-86 ( (July) ) 1963. 3. Boudin, G., et al: Les chelateurs guerissent-ils la maladie de Wilson? , La Presse Med 73:1047-1049 ( (April) ) 1965. 4. Boudin, G., and Pépin, B.: Accidents renaus dans deux cas de maladie de Wilson traités par le penicillamine , Soc Med Hop Paris 116:833-844 ( (April 30) ) 1965. 5. Goldstein, N.P., et al: Treatment of Wilson's Disease (Hepatolenticular Degeneration) With DLPenicillamine , Neurology 12:231-244 ( (April) ) 1962.Crossref 6. Goldstein, N.P.; Randall, R.V.; and Gross, J.B.: Chemical Therapy of Wilson's Disease : J Indian Med Prof 12:5399-5402 ( (July) ) 1965. 7. Michiels, J., Laterr, C. and Dumoulin, D.: Les manifestations oculaires de la maladie de Wilson traitée a la pénicillamine , Bull Soc Belg Ophtal 132:552-561, 1962. 8. Pieri, J.; Tronconi, M.; and Eisinger, P.: Conduite et surveillance du traitment par la pénicillamine au cours de la DHL et dans les intoxications: A propos de trois observations , Soc Med Hôp 100:51-57, 1963. 9. Richmond, J., et al: Hepatolenticular Degeneration (Wilson's Disease) Treated by Penicillamine , Brain 87:619-683 ( (Dec) ) 1964.Crossref 10. Sternlieb, I., and Scheinberg, I.H.: Penicillamine Therapy for Hepatolenticular Degeneration , JAMA 189:748-754 ( (Sept 7) ) 1964.Crossref 11. Sunderman, F.W., Jr.; White, J.C.; and Sunderman, F.W.: Metabolic Balance Studies in Hepatolenticular Degeneration Treated with Diethyldithiocarbamate , Amer J Med 34:875-888 ( (June) ) 1963.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Ophthalmology American Medical Association

Changes in Kayser-Fleischer Ring During Treatment of Hepatolenticular Degeneration

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Publisher
American Medical Association
Copyright
Copyright © 1968 American Medical Association. All Rights Reserved.
ISSN
0003-9950
eISSN
1538-3687
DOI
10.1001/archopht.1968.00980050624008
Publisher site
See Article on Publisher Site

Abstract

Abstract Kayser-Fleischer rings were observed in two patients over a three-year period during treatment of hepatolenticular degeneration (Wilson's disease). The clinical improvement of these patients did not correlate with changes in the corneal deposits. The neuropathologic implications of these observations are discussed. References 1. Bonamour, G., and Leopold: Le cercle vert de la cornée et la semble-cataract en fleur de tournesol dans la maladie de Wilson , Bull Soc Ophtal Lyon 7:411-414 ( (July-Aug) ) 1960. 2. Boudin, G., et al: Notre expérience du traitment de la maladie de Wilson par le penicillamine , Rev Neurolog 109:82-86 ( (July) ) 1963. 3. Boudin, G., et al: Les chelateurs guerissent-ils la maladie de Wilson? , La Presse Med 73:1047-1049 ( (April) ) 1965. 4. Boudin, G., and Pépin, B.: Accidents renaus dans deux cas de maladie de Wilson traités par le penicillamine , Soc Med Hop Paris 116:833-844 ( (April 30) ) 1965. 5. Goldstein, N.P., et al: Treatment of Wilson's Disease (Hepatolenticular Degeneration) With DLPenicillamine , Neurology 12:231-244 ( (April) ) 1962.Crossref 6. Goldstein, N.P.; Randall, R.V.; and Gross, J.B.: Chemical Therapy of Wilson's Disease : J Indian Med Prof 12:5399-5402 ( (July) ) 1965. 7. Michiels, J., Laterr, C. and Dumoulin, D.: Les manifestations oculaires de la maladie de Wilson traitée a la pénicillamine , Bull Soc Belg Ophtal 132:552-561, 1962. 8. Pieri, J.; Tronconi, M.; and Eisinger, P.: Conduite et surveillance du traitment par la pénicillamine au cours de la DHL et dans les intoxications: A propos de trois observations , Soc Med Hôp 100:51-57, 1963. 9. Richmond, J., et al: Hepatolenticular Degeneration (Wilson's Disease) Treated by Penicillamine , Brain 87:619-683 ( (Dec) ) 1964.Crossref 10. Sternlieb, I., and Scheinberg, I.H.: Penicillamine Therapy for Hepatolenticular Degeneration , JAMA 189:748-754 ( (Sept 7) ) 1964.Crossref 11. Sunderman, F.W., Jr.; White, J.C.; and Sunderman, F.W.: Metabolic Balance Studies in Hepatolenticular Degeneration Treated with Diethyldithiocarbamate , Amer J Med 34:875-888 ( (June) ) 1963.Crossref

Journal

Archives of OphthalmologyAmerican Medical Association

Published: Nov 1, 1968

References