Challenges in Testing for SARS-CoV-2 Among Patients Who Recovered From COVID-19

Challenges in Testing for SARS-CoV-2 Among Patients Who Recovered From COVID-19 Letters Editor's Note To avoid unnecessary quarantine for patients who have re- Challenges in Testing for SARS-CoV-2 covered from COVID-19, routine repeated PCR testing should Among Patients Who Recovered From COVID-19 not be done in the 90 days following infection. However, more Among patients who have recovered from COVID-19, repeated complicated is what to do about patients who are sympto- testing for SARS-CoV-2 may be done weeks or months after in- matic and have positive results on repeated PCR tests. Rein- fection either as part of routine screening (eg, screening nursing fection with SARS-CoV-2 has been documented (based on home personnel on a weekly basis to prevent transmission of in- demonstration of different genetic differences between the vi- fections to patients) or because of the development of symptoms ruses infecting the person on the first and second episode) but that are worrisome for reinfection. Unfortunately, the interpre- is rare. Until clinical laboratories have the capability to test for tation of positive test results in patients who have previously the reproductive capacity of coronavirus, interpretation of the recovered from COVID-19 is fraught. The best widely available epidemiologic significance of positive PCR results among re- test, a real-time polymerase chain reaction http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Internal Medicine American Medical Association

Challenges in Testing for SARS-CoV-2 Among Patients Who Recovered From COVID-19

JAMA Internal Medicine, Volume 181 (4) – Apr 12, 2021

Challenges in Testing for SARS-CoV-2 Among Patients Who Recovered From COVID-19

Abstract

Letters Editor's Note To avoid unnecessary quarantine for patients who have re- Challenges in Testing for SARS-CoV-2 covered from COVID-19, routine repeated PCR testing should Among Patients Who Recovered From COVID-19 not be done in the 90 days following infection. However, more Among patients who have recovered from COVID-19, repeated complicated is what to do about patients who are sympto- testing for SARS-CoV-2 may be done weeks or months after in- matic and have positive results on...
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Publisher
American Medical Association
Copyright
Copyright 2020 American Medical Association. All Rights Reserved.
ISSN
2168-6106
eISSN
2168-6114
DOI
10.1001/jamainternmed.2020.7575
Publisher site
See Article on Publisher Site

Abstract

Letters Editor's Note To avoid unnecessary quarantine for patients who have re- Challenges in Testing for SARS-CoV-2 covered from COVID-19, routine repeated PCR testing should Among Patients Who Recovered From COVID-19 not be done in the 90 days following infection. However, more Among patients who have recovered from COVID-19, repeated complicated is what to do about patients who are sympto- testing for SARS-CoV-2 may be done weeks or months after in- matic and have positive results on repeated PCR tests. Rein- fection either as part of routine screening (eg, screening nursing fection with SARS-CoV-2 has been documented (based on home personnel on a weekly basis to prevent transmission of in- demonstration of different genetic differences between the vi- fections to patients) or because of the development of symptoms ruses infecting the person on the first and second episode) but that are worrisome for reinfection. Unfortunately, the interpre- is rare. Until clinical laboratories have the capability to test for tation of positive test results in patients who have previously the reproductive capacity of coronavirus, interpretation of the recovered from COVID-19 is fraught. The best widely available epidemiologic significance of positive PCR results among re- test, a real-time polymerase chain reaction

Journal

JAMA Internal MedicineAmerican Medical Association

Published: Apr 12, 2021

References

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