Abstract The subject of oxidation presents one of the most fascinating themes in the entire domain of chemistry. The various views which have been held regarding the nature of combustion and oxidation have always exercised a profound influence on chemical thought and on biological science and medicine. Modern views regarding the nature of oxidation date from the work of Lavoisier, who observed that, in the process of oxidation, oxygen adds itself to the substance oxidized, and that the resulting one or more products weigh more than the original material by exactly the weight of oxygen required to effect the oxidation. It is not within the scope of this lecture to recount the views which have been held regarding the mechanism of oxidation in general. It would also be quite futile to review the whole subject of vital oxidation in the time at our disposal. I shall therefore confine my remarks to References 1. Kastle and Loevenhart: Am. Chem. Jour. , 1901, xxvi, 539. 2. Loevenhart: Therap. Monatsch. , 1905, p. 426. 3. Meyer, Victor: Ber. d. deutsch. chem. Gesellsch. , 1892, xxv, 2632Crossref 4. 1893, xxvi, 1354, 1727 5. 1894, xxvii, 1600. 6. Grove and Loevenhart: Jour. Pharmacol. and exper. Therap. , 1911, iii, 101. 7. Arkin: Jour. Pharmacol. and exper. Therap. , 1911, iii, 145. 8. Grove and Loevenhart: Jour. Pharmacol. and exper. Therap. , 1911, iii, 131. 9. Eyster and Loevenhart: Jour. Pharmacol. and exper. Therap. , 1913, v, 21. 10. Gasser and Loevenhart: Jour. Pharmacol. and exper. Therap. , 1914, v, 239. 11. Stewart: Jour. of Physiol. , 1894, xv, 4. 12. Loevenhart: Arch. f. d. ges. Physiol. (Pflüger's) , 1913, cl, 379.Crossref 13. Gasser and Loevenhart: Jour. of Pharmacol. and exper. Therap. , 1914, v, 239. 14. Verzár: Jour. Physiol. , 1912, xliv, 243. 15. Barcroft and Piper: Jour. of Physiol. , 1912, xliv, 359. 16. Hill, A. V.: Jour. Physiol. , 1913, xlvi, 28. 17. Bert, Paul: La pression barométrique, 1878, p. 1108 18. Compt. rend. Acad. , 1882, xciv, 805. 19. A description of this apparatus will soon be published. 20. Benedict: Deutsch. Arch. f. klin. Med. , 1912, cvii, 156. 21. Williams : Jour. Biol. Chem. , 1912, xii, 317. 22. A complete account of these experiments will soon be published. 23. Clowes and Redwood : Proc. Royal Soc. London , 1894, lvi, 2. 24. Hektoen, L.: Tr. Chicago Pathological Soc. , 1911, viii, 138. 25. Jour. Pharmacol. and exper. Therap. , 1912, iii, 223 26. Jour. Am. Med. Assn. , 1912, lix, 1598Crossref 27. Ztschr. f. d. ges. exper. Med. , 1913, ii, 19, and oral communication. 28. Jacobi, Abraham: Tr. Med. Soc., New York , 1879, p. 365.
Archives of Internal Medicine – American Medical Association
Published: Jun 1, 1915
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