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Abstract Cerebrospinal rhinorrhea is defined as a rare condition of traumatic, intracranial or unknown etiology in which there is a flow of cerebrospinal fluid by way of the nose. The first case on record was published in 1834 by King.1 In 1899 St. Clair Thomson2 gave the first good classification, and reported a series of cases. Loftus,3 in 1923, gave a comprehensive review of the literature with the report of a case, and Johnston,4 in 1926, covered the subject extensively. There are several etiologic factors. First comes trauma and next intracranial pathologic changes, such as tumors. Pressure necrosis due to hypophyseal tumors4 is an attributed cause, and necrosis of the ethmoid labyrinth as a result of infection has also been mentioned. Leber5 believed the condition to be due to hydrocephalus internus, and Loftus3 mentioned a defect of the craniopharyngeal canal; according to this theory, References 1. King: London M. & S. J. 4:823, 1834. 2. Thomson, St. Clair: The Cerebrospinal Fluid: Its Spontaneous Escape from the Nose , London, Cassell & Co., Ltd., 1899. 3. Loftus, J. E.: Laryngoscope 33:617 ( (Aug.) ) 1923. 4. Johnston, W. H.: Cerebrospinal Rhinorrhea , Ann. Otol., Rhin. & Laryng. 35:1205, 1926. 5. Leber, T.: A Case of Hydrocephalus with Postneuritic Atrophy of the Optic Nerves and Persistent Dropping of Watery Fluid from the Nose , Arch. f. Ophth. 29:273, 1833. 6. Wilson, J. Gordon: Personal communication to the authors. 7. Gutche: Dissertation, Erlangen, 1894 8. Zur Pathogenese der Hypophysistumoren und über den nasalen Abfluss, so wie das Verhalten des Liquor cerebrospinalis , Centralbl. f. Laryng. 11:460, 1895. 9. Learmonth, J. R.: Cerebrospinal Rhinorrhea Treated by Operation , Proc. Staff Meet., Mayo Clin. 4:115 ( (April 10) 1929.
Archives of Otolaryngology – American Medical Association
Published: Nov 1, 1931
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