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CEREBRAL DAMAGE IN A CASE OF FATAL POISONING DUE TO A COMPOUND OF ERGOT AND APIOL (ERGOAPIOL)

CEREBRAL DAMAGE IN A CASE OF FATAL POISONING DUE TO A COMPOUND OF ERGOT AND APIOL (ERGOAPIOL) Numerous cases of apiol poisoning have been reported in recent years. In the majority the symptoms were those of polyneuritis or nephritis. Cerebral involvement has been rare. I here report the changes in the brain in a fatal case: History.— E. R., a white woman, aged 20, was admitted to the University of Michigan Hospital in coma, which had developed forty-eight hours previously. Four days prior to admission the patient took seventeen capsules of ergoapiol 1 to induce abortion. The next evening she became nauseated, collapsed and had convulsions. Examination.— The patient was well developed. The lips and mouth were ulcerated and bleeding from continued biting. The breasts were full and firm, and colostrum could be expressed. There were soft systolic murmurs at the apical and pulmonary areas. The abdomen was soft. The introitus vaginae was slightly congested. There was paronychia of the left great toe. The temperature was 104.6 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

CEREBRAL DAMAGE IN A CASE OF FATAL POISONING DUE TO A COMPOUND OF ERGOT AND APIOL (ERGOAPIOL)

JAMA , Volume 110 (8) – Feb 19, 1938

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References (1)

Publisher
American Medical Association
Copyright
Copyright © 1938 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.1938.62790080001009
Publisher site
See Article on Publisher Site

Abstract

Numerous cases of apiol poisoning have been reported in recent years. In the majority the symptoms were those of polyneuritis or nephritis. Cerebral involvement has been rare. I here report the changes in the brain in a fatal case: History.— E. R., a white woman, aged 20, was admitted to the University of Michigan Hospital in coma, which had developed forty-eight hours previously. Four days prior to admission the patient took seventeen capsules of ergoapiol 1 to induce abortion. The next evening she became nauseated, collapsed and had convulsions. Examination.— The patient was well developed. The lips and mouth were ulcerated and bleeding from continued biting. The breasts were full and firm, and colostrum could be expressed. There were soft systolic murmurs at the apical and pulmonary areas. The abdomen was soft. The introitus vaginae was slightly congested. There was paronychia of the left great toe. The temperature was 104.6

Journal

JAMAAmerican Medical Association

Published: Feb 19, 1938

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