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CEREBRAL ABSCESS (PARADOXIC) ACCOMPANYING CONGENITAL HEART DISEASE: REPORT OF TWO CASES

CEREBRAL ABSCESS (PARADOXIC) ACCOMPANYING CONGENITAL HEART DISEASE: REPORT OF TWO CASES Abstract Cerebral abscess occurring in patients with congenital disease of the heart is rare and not commonly recognized. There are early recorded observations of cerebral abscess in patients dying with congenital heart disease, but it was not until 1880 that Ballet1 first made clear the relationship of these two morbid conditions. The incidence of congenital heart disease varies considerably in the necropsy observations reported from different institutions. For example, 75 cases of this anomaly reported by Leech2 from the Johns Hopkins Hospital constituted 1.29 per cent of all the cases in which necropsy was done, whereas the 105 cases of congenital anomalies of the heart or the great vessels reported by Gibson3 from the cardiac service of the Children's Memorial Hospital were 5.4 per cent of the 1,950 cases of infants on whom autopsy was performed. Cerebral abscess as a complication is not mentioned by either author. All References 1. Ballet, G.: Des abscés du cerveau consécutifs á certaines malformations cardiaques , Arch. gén. de méd. 5:659, 1880. 2. Leech, C. B.: Congenital Heart Disease: Clinical Analysis of Seventy-Five Cases from Johns Hopkins Hospital , J. Pediat. 7:808-839 ( (Dec.) ) 1935.Crossref 3. Gibson, S., and Clifton, W. M.: Congenital Heart Disease: Clinical and Postmortem Study of One Hundred and Five Cases , Am. J. Dis. Child. 55:761-767 ( (April) ) 1938.Crossref 4. Gowers, W. R: A Manual of Diseases of the Nervous System , London, J. & A. Churchill, 1888, vol. 2, p. 443. 5. Osler, W.: The Principles and Practice of Medicine , ed. 8, New York, D. Appleton and Company, 1912. 6. Abbott, M. E.; Lewis, D. S., and Beattie, W. W.: Differential Study of a Case of Pulmonary Stenosis of Inflammatory Origin (Ventricular Septum Closed) and Two Cases of (a) Pulmonary Stenosis, and (b) Pulmonary Atresia with Associated Ventricular Septal Defect and Death from Paradoxical Cerebral Embolism , Am. J. M. Sc. 165:636-659 ( (May) ) 1923.Crossref 7. Abbott, M. E.: Congenital Heart Disease , in Nelson's New Loose-Leaf Living Medicine , New York, Thomas Nelson & Sons, 1927, vol. 4, pp. 207-321. 8. Rabinowitz, M. A.; Weinstein, J., and Marcus, I. H.: Brain Abscess (Paradoxical) in Congenital Heart Disease , Am. Heart J. 7:790-795 ( (Aug.) ) 1932.Crossref 9. Ingham, D. W.: Paradoxical Embolism, (with Patent Foramen Ovale) , Am. J. M. Sc. 196:201-207 ( (Aug.) ) 1938.Crossref 10. Bach, F.: A Case of Congenital Morbus Cordis Studied Over a Period of Twelve Years , Lancet 1:1009-1011 ( (May 19) ) 1928.Crossref 11. Baumgartner, E. A., and Abbott, M. E.: Interventricular Septal Defect with Dextroposition of Aorta and Dilatation of the Pulmonary Artery ("Eisenmenger Complex") Terminating by Cerebral Abscess , Am. J. M. Sc. 177:639647 ( (May) ) 1929.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Internal Medicine American Medical Association

CEREBRAL ABSCESS (PARADOXIC) ACCOMPANYING CONGENITAL HEART DISEASE: REPORT OF TWO CASES

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Publisher
American Medical Association
Copyright
Copyright © 1940 American Medical Association. All Rights Reserved.
ISSN
0730-188X
DOI
10.1001/archinte.1940.00190180094007
Publisher site
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Abstract

Abstract Cerebral abscess occurring in patients with congenital disease of the heart is rare and not commonly recognized. There are early recorded observations of cerebral abscess in patients dying with congenital heart disease, but it was not until 1880 that Ballet1 first made clear the relationship of these two morbid conditions. The incidence of congenital heart disease varies considerably in the necropsy observations reported from different institutions. For example, 75 cases of this anomaly reported by Leech2 from the Johns Hopkins Hospital constituted 1.29 per cent of all the cases in which necropsy was done, whereas the 105 cases of congenital anomalies of the heart or the great vessels reported by Gibson3 from the cardiac service of the Children's Memorial Hospital were 5.4 per cent of the 1,950 cases of infants on whom autopsy was performed. Cerebral abscess as a complication is not mentioned by either author. All References 1. Ballet, G.: Des abscés du cerveau consécutifs á certaines malformations cardiaques , Arch. gén. de méd. 5:659, 1880. 2. Leech, C. B.: Congenital Heart Disease: Clinical Analysis of Seventy-Five Cases from Johns Hopkins Hospital , J. Pediat. 7:808-839 ( (Dec.) ) 1935.Crossref 3. Gibson, S., and Clifton, W. M.: Congenital Heart Disease: Clinical and Postmortem Study of One Hundred and Five Cases , Am. J. Dis. Child. 55:761-767 ( (April) ) 1938.Crossref 4. Gowers, W. R: A Manual of Diseases of the Nervous System , London, J. & A. Churchill, 1888, vol. 2, p. 443. 5. Osler, W.: The Principles and Practice of Medicine , ed. 8, New York, D. Appleton and Company, 1912. 6. Abbott, M. E.; Lewis, D. S., and Beattie, W. W.: Differential Study of a Case of Pulmonary Stenosis of Inflammatory Origin (Ventricular Septum Closed) and Two Cases of (a) Pulmonary Stenosis, and (b) Pulmonary Atresia with Associated Ventricular Septal Defect and Death from Paradoxical Cerebral Embolism , Am. J. M. Sc. 165:636-659 ( (May) ) 1923.Crossref 7. Abbott, M. E.: Congenital Heart Disease , in Nelson's New Loose-Leaf Living Medicine , New York, Thomas Nelson & Sons, 1927, vol. 4, pp. 207-321. 8. Rabinowitz, M. A.; Weinstein, J., and Marcus, I. H.: Brain Abscess (Paradoxical) in Congenital Heart Disease , Am. Heart J. 7:790-795 ( (Aug.) ) 1932.Crossref 9. Ingham, D. W.: Paradoxical Embolism, (with Patent Foramen Ovale) , Am. J. M. Sc. 196:201-207 ( (Aug.) ) 1938.Crossref 10. Bach, F.: A Case of Congenital Morbus Cordis Studied Over a Period of Twelve Years , Lancet 1:1009-1011 ( (May 19) ) 1928.Crossref 11. Baumgartner, E. A., and Abbott, M. E.: Interventricular Septal Defect with Dextroposition of Aorta and Dilatation of the Pulmonary Artery ("Eisenmenger Complex") Terminating by Cerebral Abscess , Am. J. M. Sc. 177:639647 ( (May) ) 1929.Crossref

Journal

Archives of Internal MedicineAmerican Medical Association

Published: Dec 1, 1940

References