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Central Mucoepidermoid Carcinoma of the Mandible

Central Mucoepidermoid Carcinoma of the Mandible CLINICAL NOTE Tumorigenesis Within a Keratocyst F. Christopher Holsinger, MD; Jonathan M. Owens, MD; A. Kevin Raymond, MD; Jeffrey N. Myers, MD, PhD ucoepidermoid carcinomas account for 15% of all salivary gland tumors. The vast majority (60%) occur in the parotid gland, with the remainder arising in the sub- mandibular gland and minor salivary glands. Mucoepidermoid carcinoma arising M within the maxilla or mandible, known as central mucoepidermoid carcinoma (CMC), is a far less common entity, with fewer than 200 cases reported in the English-language literature. The pathogenesis of CMC remains con- bacco or consumption of alcohol. On troversial. Heterotopic rests of normal sali- physical examination, a submucosal le- vary gland tissue are found commonly in sion was noted on the buccal surface of the many sites, including the mandible. Sev- mandible extending from the first premo- eral theories of their origin have been pos- lar to the angle of the mandible where the tulated : (1) entrapment of retromolar mu- initial surgery had been performed. No cous glands within the mandible, (2) other oral lesions were noted. No pal- developmentally included embryonic rem- pable cervical adenopathy was present. All nants of submandibular glands within the cranial nerves were http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Otolaryngology - Head & Neck Surgery American Medical Association

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Publisher
American Medical Association
Copyright
Copyright 2002 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
2168-6181
eISSN
2168-619X
DOI
10.1001/archotol.128.6.718
Publisher site
See Article on Publisher Site

Abstract

CLINICAL NOTE Tumorigenesis Within a Keratocyst F. Christopher Holsinger, MD; Jonathan M. Owens, MD; A. Kevin Raymond, MD; Jeffrey N. Myers, MD, PhD ucoepidermoid carcinomas account for 15% of all salivary gland tumors. The vast majority (60%) occur in the parotid gland, with the remainder arising in the sub- mandibular gland and minor salivary glands. Mucoepidermoid carcinoma arising M within the maxilla or mandible, known as central mucoepidermoid carcinoma (CMC), is a far less common entity, with fewer than 200 cases reported in the English-language literature. The pathogenesis of CMC remains con- bacco or consumption of alcohol. On troversial. Heterotopic rests of normal sali- physical examination, a submucosal le- vary gland tissue are found commonly in sion was noted on the buccal surface of the many sites, including the mandible. Sev- mandible extending from the first premo- eral theories of their origin have been pos- lar to the angle of the mandible where the tulated : (1) entrapment of retromolar mu- initial surgery had been performed. No cous glands within the mandible, (2) other oral lesions were noted. No pal- developmentally included embryonic rem- pable cervical adenopathy was present. All nants of submandibular glands within the cranial nerves were

Journal

JAMA Otolaryngology - Head & Neck SurgeryAmerican Medical Association

Published: Jun 1, 2002

References