Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Caution Urged in Exchange Transfusions for Infants

Caution Urged in Exchange Transfusions for Infants Measurementlbumin is a more satisfactory means of determining when exchange transfusions should be done in infants to avoid kernicterus than the standard method of measuring unconjugated bilirubin levels in the blood, a Berkeley, Calif, pediatrician told the Annual AMA Convention. Criteria for exchange transfusion have been under debate since the technique was introduced around 1953 as a means of reducing the incidence of kernicterus due to erythroblastosis, Virginia Y. Blacklidge, MD, told a Convention symposium on jaundice. "A statistical analysis of the incidence of kernicterus in relation to the maximum serum bilirubin led to the establishment of the magic figure of 20 mg/100ml as the upper tolerable limit." This figure is not, however, a reliable indicator of the possibility of kernicterus, Blacklidge said. Kernicterus has been reported at much lower levels of bilirubin and both term and premature infants have tolerated much higher levels. "Variations in the reliability and reproducibility http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

Caution Urged in Exchange Transfusions for Infants

JAMA , Volume 189 (4) – Jul 27, 1964
Download PDF
2 pages

Loading next page...
 
/lp/american-medical-association/caution-urged-in-exchange-transfusions-for-infants-PAaEzT5P6G

References (0)

References for this paper are not available at this time. We will be adding them shortly, thank you for your patience.

Publisher
American Medical Association
Copyright
Copyright © 1964 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.1964.03070040095046
Publisher site
See Article on Publisher Site

Abstract

Measurementlbumin is a more satisfactory means of determining when exchange transfusions should be done in infants to avoid kernicterus than the standard method of measuring unconjugated bilirubin levels in the blood, a Berkeley, Calif, pediatrician told the Annual AMA Convention. Criteria for exchange transfusion have been under debate since the technique was introduced around 1953 as a means of reducing the incidence of kernicterus due to erythroblastosis, Virginia Y. Blacklidge, MD, told a Convention symposium on jaundice. "A statistical analysis of the incidence of kernicterus in relation to the maximum serum bilirubin led to the establishment of the magic figure of 20 mg/100ml as the upper tolerable limit." This figure is not, however, a reliable indicator of the possibility of kernicterus, Blacklidge said. Kernicterus has been reported at much lower levels of bilirubin and both term and premature infants have tolerated much higher levels. "Variations in the reliability and reproducibility

Journal

JAMA – American Medical Association

Published: Jul 27, 1964

There are no references for this article.