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Cataracts in Rheumatoid Arthritis Patients Treated with Corticosteroids: Description and Differential Diagnosis

Cataracts in Rheumatoid Arthritis Patients Treated with Corticosteroids: Description and... Abstract A previous report by us1 has detailed the occurrence of posterior subcapsular cataracts (PSC) in 5 of 22 (23%) rheumatoid arthritis patients treated with 10-16 mg. of prednisone or its equivalent daily for one year or more and in 12 of 16 (75%) treated with 16 mg. or more. The age of the patients and the duration and severity of rheumatoid arthritis showed no significant correlation with the development of cataracts, and since no cataract of this type was seen in 19 rheumatoid arthritis patients who were not treated with corticosteroids, it was suggested that corticosteroids were the chief etiological factor. It is the purpose of this paper to delineate and discuss the cataracts of the above 17 patients from an ophthalmologic orientation. Material and Methods The population was composed of 5 females and 12 males, ranging in age from 34 to 61 years. References 1. Black, R. L.; Oglesby, R. B.; von Sallmann, L., and Bunim, J. J.: Posterior Subcapsular Cataracts Induced by Corticosteroids in Patients with Rheumatoid Arthritis , J.A.M.A. 174:166, 1960.Crossref 2. O'Brien, C. S.; Molsberry, J. M., and Allen, J. H.: Diabetic Cataract , J.A.M.A. 103:892, 1934.Crossref 3. Horner, W. D.; Jones, R. B., and Boardman, N. W.: Cataracts Following the Use of Dinitrophenol , J.A.M.A. 105:108, 1935.Crossref 4. Bellows, J. G.: Cataract and Anomalies of the Lens , St. Louis, The C. V. Mosby Company, 1944. 5. Vogt, A.: Lehrbuch und Atlas der Spaltlampenmikroskopie des lebenden Auges , Berlin, J. Springer, 1931. 6. Cogan, D. G.; Donaldson, D. D., and Reese, A. B.: Clinical and Pathological Characteristics of Radiation Cataract , A.M.A. Arch. Ophthal. 47:55, 1952.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Ophthalmology American Medical Association

Cataracts in Rheumatoid Arthritis Patients Treated with Corticosteroids: Description and Differential Diagnosis

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Publisher
American Medical Association
Copyright
Copyright © 1961 American Medical Association. All Rights Reserved.
ISSN
0003-9950
eISSN
1538-3687
DOI
10.1001/archopht.1961.00960010521013
Publisher site
See Article on Publisher Site

Abstract

Abstract A previous report by us1 has detailed the occurrence of posterior subcapsular cataracts (PSC) in 5 of 22 (23%) rheumatoid arthritis patients treated with 10-16 mg. of prednisone or its equivalent daily for one year or more and in 12 of 16 (75%) treated with 16 mg. or more. The age of the patients and the duration and severity of rheumatoid arthritis showed no significant correlation with the development of cataracts, and since no cataract of this type was seen in 19 rheumatoid arthritis patients who were not treated with corticosteroids, it was suggested that corticosteroids were the chief etiological factor. It is the purpose of this paper to delineate and discuss the cataracts of the above 17 patients from an ophthalmologic orientation. Material and Methods The population was composed of 5 females and 12 males, ranging in age from 34 to 61 years. References 1. Black, R. L.; Oglesby, R. B.; von Sallmann, L., and Bunim, J. J.: Posterior Subcapsular Cataracts Induced by Corticosteroids in Patients with Rheumatoid Arthritis , J.A.M.A. 174:166, 1960.Crossref 2. O'Brien, C. S.; Molsberry, J. M., and Allen, J. H.: Diabetic Cataract , J.A.M.A. 103:892, 1934.Crossref 3. Horner, W. D.; Jones, R. B., and Boardman, N. W.: Cataracts Following the Use of Dinitrophenol , J.A.M.A. 105:108, 1935.Crossref 4. Bellows, J. G.: Cataract and Anomalies of the Lens , St. Louis, The C. V. Mosby Company, 1944. 5. Vogt, A.: Lehrbuch und Atlas der Spaltlampenmikroskopie des lebenden Auges , Berlin, J. Springer, 1931. 6. Cogan, D. G.; Donaldson, D. D., and Reese, A. B.: Clinical and Pathological Characteristics of Radiation Cataract , A.M.A. Arch. Ophthal. 47:55, 1952.Crossref

Journal

Archives of OphthalmologyAmerican Medical Association

Published: Oct 1, 1961

References