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CARNOSINE OF THE OCULAR TISSUES

CARNOSINE OF THE OCULAR TISSUES Abstract Since the normal biochemistry of the ocular tissues is practically unknown, it is difficult to determine the course of events leading to pathologic changes. One method of studying the biochemistry of a tissue is to analyze the tissues and to determine quantitatively the amounts of the various major constituents. In a previous series of articles,1 too numerous to mention here, the results of the analyses of two major constituents of the ocular tissues, i. e., the proteins and the lipids, were reported. During the past two years interest was turned toward an inquiry into the nature of the third constituent, the water-soluble extractives. In most of the ocular tissues these substances occur in minute quantities and are difficult to isolate and identify chemically. Frequently the water-soluble extractives can be determined only quantitatively, one at a time, in the tissues. Consequently the investigation may be limited to a few References 1. Krause, A. C.: The Biochemistry of the Eye , Baltimore, Johns Hopkins Press, 1934. 2. Eggleston, M. G., and Eggleston, P.: Carnosine in Amphibian Voluntary Muscle , Quart. J. Exper. Physiol. 23:391, 1933. 3. Koessler, K. K., and Hanke, M. T.: A Microchemical Colorimetric Method for Estimating Imidazole Derivatives , J. Biol. Chem. 39:497, 1919. 4. Wilson, D. W., and Wolff, W. A.: The Determination of Anserine in Muscle , .J. Biol. Chem. 100:cvi, 1933. 5. Folin, O., and Marenzi, A. D.: Tyrosine and Triptophane Determinations in One-Tenth Gram of Protein , J. Biol. Chem. 83:89, 1929. 6. Gulewitsch, W., and Amiradžibi, S.: Zur Kenntnis der Extractivstoffe der Muskeln , Ztschr. f. physiol. Chem. 30:565, 1900.Crossref 7. Ackermann, D.; Timpe, O., and Poller, K.: Ueber das Anserin, einen neuen Bestandteil der Vogelmuskulatur , Ztschr. f. physiol. Chem. 183:1, 1929.Crossref 8. Wolff, W. A., and Wilson, D. W.: Anserine in Mammalian Skeletal Muscle , J. Biol. Chem. 95:495, 1932 9. Carnosine and Anserine in Mammalian Skeletal Muscle , Wolff Anserine in Mammalian Skeletal Muscle 109:565, 1935. 10. Rasenkow, I. P.; Derweis, G. W., and Ssewerin, S. E.: Zur Frage nach Carnosinwirkung auf die Magensaftsekretion , Ztschr. f. physiol. Chem. 162:95, 1926.Crossref 11. Blanchetière, M. A.: Constitution des anhydrides des acides aspartique et glutamique; son importance biologique , Bull. Soc. chim. biol. 6:854, 1924. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Ophthalmology American Medical Association

CARNOSINE OF THE OCULAR TISSUES

Archives of Ophthalmology , Volume 16 (6) – Dec 1, 1936

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Publisher
American Medical Association
Copyright
Copyright © 1936 American Medical Association. All Rights Reserved.
ISSN
0003-9950
eISSN
1538-3687
DOI
10.1001/archopht.1936.00840240086008
Publisher site
See Article on Publisher Site

Abstract

Abstract Since the normal biochemistry of the ocular tissues is practically unknown, it is difficult to determine the course of events leading to pathologic changes. One method of studying the biochemistry of a tissue is to analyze the tissues and to determine quantitatively the amounts of the various major constituents. In a previous series of articles,1 too numerous to mention here, the results of the analyses of two major constituents of the ocular tissues, i. e., the proteins and the lipids, were reported. During the past two years interest was turned toward an inquiry into the nature of the third constituent, the water-soluble extractives. In most of the ocular tissues these substances occur in minute quantities and are difficult to isolate and identify chemically. Frequently the water-soluble extractives can be determined only quantitatively, one at a time, in the tissues. Consequently the investigation may be limited to a few References 1. Krause, A. C.: The Biochemistry of the Eye , Baltimore, Johns Hopkins Press, 1934. 2. Eggleston, M. G., and Eggleston, P.: Carnosine in Amphibian Voluntary Muscle , Quart. J. Exper. Physiol. 23:391, 1933. 3. Koessler, K. K., and Hanke, M. T.: A Microchemical Colorimetric Method for Estimating Imidazole Derivatives , J. Biol. Chem. 39:497, 1919. 4. Wilson, D. W., and Wolff, W. A.: The Determination of Anserine in Muscle , .J. Biol. Chem. 100:cvi, 1933. 5. Folin, O., and Marenzi, A. D.: Tyrosine and Triptophane Determinations in One-Tenth Gram of Protein , J. Biol. Chem. 83:89, 1929. 6. Gulewitsch, W., and Amiradžibi, S.: Zur Kenntnis der Extractivstoffe der Muskeln , Ztschr. f. physiol. Chem. 30:565, 1900.Crossref 7. Ackermann, D.; Timpe, O., and Poller, K.: Ueber das Anserin, einen neuen Bestandteil der Vogelmuskulatur , Ztschr. f. physiol. Chem. 183:1, 1929.Crossref 8. Wolff, W. A., and Wilson, D. W.: Anserine in Mammalian Skeletal Muscle , J. Biol. Chem. 95:495, 1932 9. Carnosine and Anserine in Mammalian Skeletal Muscle , Wolff Anserine in Mammalian Skeletal Muscle 109:565, 1935. 10. Rasenkow, I. P.; Derweis, G. W., and Ssewerin, S. E.: Zur Frage nach Carnosinwirkung auf die Magensaftsekretion , Ztschr. f. physiol. Chem. 162:95, 1926.Crossref 11. Blanchetière, M. A.: Constitution des anhydrides des acides aspartique et glutamique; son importance biologique , Bull. Soc. chim. biol. 6:854, 1924.

Journal

Archives of OphthalmologyAmerican Medical Association

Published: Dec 1, 1936

References

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