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CARDIAC OUTPUT: ITS RELATED FUNCTIONS IN A CASE OF COARCTATION OF THE AORTA

CARDIAC OUTPUT: ITS RELATED FUNCTIONS IN A CASE OF COARCTATION OF THE AORTA Abstract Coarctation of the aorta presents several features of interest concerning the hemodynamics and regulation of the circulation, for it presents a condition in which the brain and carotid sinus, the chief sites of any central regulatory functions, are subjected to an arterial hypertension while the lower extremities and viscera are supplied with blood at a lower pressure. The cardiac output has not hitherto been studied in cases of coarctation. Because of the relative infrequency with which the condition is recognized in young persons before the advent of secondary complications, and because of the interesting theoretical considerations involved, the results obtained in a single person have been considered worthy of a report. REPORT OF A CASE Clinical History. —The subject of our study, J. P. F., Jr., was a medical student, 25 years of age. His family and past history were entirely irrelevant. Except for diphtheria, measles, chickenpox and occasional colds, References 1. Abbott, M. E.: Coarctation of the Aorta , in Osler, William, and McCrae, Thomas: Modern Medicine , ed. 3, Philadelphia, Lea & Febiger, 1927, vol. 4, p. 772. 2. Blackford, L. M.: Coarctation of the Aorta , Arch. Int. Med. 41:702 ( (May) ) 1928.Crossref 3. Eppinger, E. C., and Midelfart, P. A. H.: Stenosis of the Isthmus (Coarctation of the Aorta) , Am. J. M. Sc. 185:528, 1933.Crossref 4. Evans, W.: Congenital Stenosis (Coarctation), Atresia, and Interruption of the Aortic Arch , Quart. J. Med. 2:1 ( (Jan.) ) 1933.Crossref 5. King, J. T., Jr.: Stenosis of the Isthmus (Coarctation) of the Aorta and Its Diagnosis During Life , Arch. Int. Med. 38:69 ( (July) ) 1926.Crossref 6. Grollman, A.: The Cardiac Output of Man in Health and Disease , Springfield, Ill., Charles C. Thomas, Publisher, 1932. 7. DuBois, E. F.: Basal Metabolism in Health and Disease , ed. 2, Philadelphia, Lea & Febiger, 1927. 8. Blumgart, H. L., Lawrence, J. S., and Ernstene, A. C.: The Dynamics of the Circulation in Coarctation (Stenosis of the Isthmus) of the Aorta of the Adult Type , Arch. Int. Med. 47:806 ( (May) ) 1931.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Internal Medicine American Medical Association

CARDIAC OUTPUT: ITS RELATED FUNCTIONS IN A CASE OF COARCTATION OF THE AORTA

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Publisher
American Medical Association
Copyright
Copyright © 1934 American Medical Association. All Rights Reserved.
ISSN
0730-188X
DOI
10.1001/archinte.1934.00160070040002
Publisher site
See Article on Publisher Site

Abstract

Abstract Coarctation of the aorta presents several features of interest concerning the hemodynamics and regulation of the circulation, for it presents a condition in which the brain and carotid sinus, the chief sites of any central regulatory functions, are subjected to an arterial hypertension while the lower extremities and viscera are supplied with blood at a lower pressure. The cardiac output has not hitherto been studied in cases of coarctation. Because of the relative infrequency with which the condition is recognized in young persons before the advent of secondary complications, and because of the interesting theoretical considerations involved, the results obtained in a single person have been considered worthy of a report. REPORT OF A CASE Clinical History. —The subject of our study, J. P. F., Jr., was a medical student, 25 years of age. His family and past history were entirely irrelevant. Except for diphtheria, measles, chickenpox and occasional colds, References 1. Abbott, M. E.: Coarctation of the Aorta , in Osler, William, and McCrae, Thomas: Modern Medicine , ed. 3, Philadelphia, Lea & Febiger, 1927, vol. 4, p. 772. 2. Blackford, L. M.: Coarctation of the Aorta , Arch. Int. Med. 41:702 ( (May) ) 1928.Crossref 3. Eppinger, E. C., and Midelfart, P. A. H.: Stenosis of the Isthmus (Coarctation of the Aorta) , Am. J. M. Sc. 185:528, 1933.Crossref 4. Evans, W.: Congenital Stenosis (Coarctation), Atresia, and Interruption of the Aortic Arch , Quart. J. Med. 2:1 ( (Jan.) ) 1933.Crossref 5. King, J. T., Jr.: Stenosis of the Isthmus (Coarctation) of the Aorta and Its Diagnosis During Life , Arch. Int. Med. 38:69 ( (July) ) 1926.Crossref 6. Grollman, A.: The Cardiac Output of Man in Health and Disease , Springfield, Ill., Charles C. Thomas, Publisher, 1932. 7. DuBois, E. F.: Basal Metabolism in Health and Disease , ed. 2, Philadelphia, Lea & Febiger, 1927. 8. Blumgart, H. L., Lawrence, J. S., and Ernstene, A. C.: The Dynamics of the Circulation in Coarctation (Stenosis of the Isthmus) of the Aorta of the Adult Type , Arch. Int. Med. 47:806 ( (May) ) 1931.Crossref

Journal

Archives of Internal MedicineAmerican Medical Association

Published: Jan 1, 1934

References