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Cardiac Myxoma: Surgical Treatment in Four Cases

Cardiac Myxoma: Surgical Treatment in Four Cases Abstract Primary tumors of the heart, although rare, are being recognized more frequently as a result of increasing interest in cardiovascular surgery and improvement in diagnostic techniques. Intracardiac myxomata comprise some 50% of primary cardiac tumors and are located in the left atrium in approximately 75% of cases. Myxomata occur in persons of all ages, including the newborn, but the majority of patients are between 30 and 60 years of age. The lesion occurs in females three times as frequently as in males. Although the majority of these lesions arise at the fossa ovalis, in some cases the point of attachment is the valve of the inferior vena cava and the left ventricle. Tumors of the heart drew the attention of pathologists as early as the 17th century, as evidenced by the writings of Malpighi, in 1666, in "De polypo cordis dissertatio," and many others, quoted at length in the monograph References 1. Bahnson, H. T.; Spencer, F. C., and Andrus, E. C.: Diagnosis and Treatment of Intracavitary Myxomas of the Heart , Ann. Surg. 145:915, 1957.Crossref 2. Bigelow, W. G.; Dolan, F. G., and Campbell, F, W.: Effect of Hypothermia upon the Risk of Surgery, XVI Congress Internationale dc Chirurgie, Brussels, 1955. 3. Brock, R.: Surgical Approach to the Left Atrium: Removal of an Atrial Myxoma , Guy's Hosp. Rep. 105:382, 1956. 4. Chin, E. F., and Ross, D. N.: Myxoma of the Left Atrium: Successful Surgical Removal Under Hypothermia , Brit. M. J. 1:1447, 1957.Crossref 5. Clowes, G. H. A., Jr.; Neville, W. E.; Hopkins, A.; Anzola, J., and Simione, F. A.: Factors Contributing to Success or Failure in Use of Pump Oxygenator for Complete By-Pass of the Heart and Lung: Experimental and Surgical , Surgery 36:557, 1954. 6. Coates, E. O., Jr., and Drake, E. H.: Myxoma of the Right Atrium, with Variable Right-to-Left Shunt: Clinical and Physiologic Observations and Report of a Case with Successful Operative Removal , New England J. Med. 259:165, 1958.Crossref 7. Crafoord, C., in discussion in Henry Ford Hospital International Symposium on Cardiovascular Surgery , edited by C. R. Lam, Philadelphia, W. B. Saunders Company, 1955, p. 202. 8. Fatti, L., in discussion on Scannell and Grillo.22 9. Fell, E. H., in discussion on Scannell and Grillo.22 9. Goldberg, H. P.; Glenn, F.; Dotter, C. T., and Steinberg, I.: Myxoma of the Left Atrium: Diagnosis Made During Life with Operative and Postmortem Findings , Circulation 6:762, 1952.Crossref 10. Hanlon, R., in discussion on Bahnson and others.1 11. Hopkins, W. A., in discussion on Scannell and Grillo.22 12. Likoff, W.; Geckeler, G. D., and Gregory, J. E.: Functional Mitral Stenosis Produced by an Intra-Atrial Tumor , Am. Heart J. 47:619, 1954.Crossref 13. Lyons, H. A.; Kelly, J. J., Jr.; Nusbaum, N., and Dennis, C.: Right Atrial Myxoma: A Clinical Study of a Patient in Whom Diagnosis Was Made by Angiocardiography During Life (Surgically Removed) , Am. J. Med. 25:321, 1958.Crossref 14. Mahaim, I.: Les tumeurs et les polypes du cœur: Étude anatamo-clinique , Paris, Masson & Cie, 1945. 15. Nichols, H. T.: The Removal of Benign Pedunculated Intra-Atrial Tumors: A Closed Surgical Approach , J. Thoracic Surg. 31:739, 1956. 16. Paquet, E.: The Diagnostic Approach to Auricular Myxomas , Canad. M. A. J. 74:121, 1956. 17. Prichard, R. W.: Tumors of the Heart: Review of the Subject and Report of 150 Cases , A. M. A. Arch. Path. 51:98, 1951. 18. Ravid, J. M., and Sachs, J.: Tumors of the Heart, with Report of Primary Fibromyxosarcoma of the Left Auricle and Pulmonary Vein, Associated with Multiple Tumors of the Mesentery and Gastrointestinal Tract , Am. Heart J. 26:385, 1943.Crossref 19. Ribbert, M. W. H.: Geschwulstlehre fiir Aerzte und Studierende , Bonn, F. Cohen, 1904, p. 230 20. Robertson, R., in discussion on Scannell and Grillo.22 21. Scannell, J. G., and Grillo, H. C.: Primary Tumors of the Heart, a Surgical Problem , J. Thoracic Surg. 35:23, 1958. 22. Steinberg, I.; Dotter, C. T., and Glenn, F.: Myxoma of Heart: Roentgen Diagnosis During Life in 3 Cases , Dis. Chest 24:509, 1953.Crossref 23. Stout, A. P.: Myxoma, the Tumor of Primitive Mesenchyme , Ann. Surg. 127:706, 1948.Crossref 24. Thorel, C.: Geschwülste des Herzens , ergebn. allg. Path. u. path. Anat. 17: ( (Pt. 2) ):677, 1915. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png A.M.A. Archives Surgery American Medical Association

Cardiac Myxoma: Surgical Treatment in Four Cases

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Publisher
American Medical Association
Copyright
Copyright © 1959 American Medical Association. All Rights Reserved.
ISSN
0096-6908
DOI
10.1001/archsurg.1959.04320030054010
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Abstract

Abstract Primary tumors of the heart, although rare, are being recognized more frequently as a result of increasing interest in cardiovascular surgery and improvement in diagnostic techniques. Intracardiac myxomata comprise some 50% of primary cardiac tumors and are located in the left atrium in approximately 75% of cases. Myxomata occur in persons of all ages, including the newborn, but the majority of patients are between 30 and 60 years of age. The lesion occurs in females three times as frequently as in males. Although the majority of these lesions arise at the fossa ovalis, in some cases the point of attachment is the valve of the inferior vena cava and the left ventricle. Tumors of the heart drew the attention of pathologists as early as the 17th century, as evidenced by the writings of Malpighi, in 1666, in "De polypo cordis dissertatio," and many others, quoted at length in the monograph References 1. Bahnson, H. T.; Spencer, F. C., and Andrus, E. C.: Diagnosis and Treatment of Intracavitary Myxomas of the Heart , Ann. Surg. 145:915, 1957.Crossref 2. Bigelow, W. G.; Dolan, F. G., and Campbell, F, W.: Effect of Hypothermia upon the Risk of Surgery, XVI Congress Internationale dc Chirurgie, Brussels, 1955. 3. Brock, R.: Surgical Approach to the Left Atrium: Removal of an Atrial Myxoma , Guy's Hosp. Rep. 105:382, 1956. 4. Chin, E. F., and Ross, D. N.: Myxoma of the Left Atrium: Successful Surgical Removal Under Hypothermia , Brit. M. J. 1:1447, 1957.Crossref 5. Clowes, G. H. A., Jr.; Neville, W. E.; Hopkins, A.; Anzola, J., and Simione, F. A.: Factors Contributing to Success or Failure in Use of Pump Oxygenator for Complete By-Pass of the Heart and Lung: Experimental and Surgical , Surgery 36:557, 1954. 6. Coates, E. O., Jr., and Drake, E. H.: Myxoma of the Right Atrium, with Variable Right-to-Left Shunt: Clinical and Physiologic Observations and Report of a Case with Successful Operative Removal , New England J. Med. 259:165, 1958.Crossref 7. Crafoord, C., in discussion in Henry Ford Hospital International Symposium on Cardiovascular Surgery , edited by C. R. Lam, Philadelphia, W. B. Saunders Company, 1955, p. 202. 8. Fatti, L., in discussion on Scannell and Grillo.22 9. Fell, E. H., in discussion on Scannell and Grillo.22 9. Goldberg, H. P.; Glenn, F.; Dotter, C. T., and Steinberg, I.: Myxoma of the Left Atrium: Diagnosis Made During Life with Operative and Postmortem Findings , Circulation 6:762, 1952.Crossref 10. Hanlon, R., in discussion on Bahnson and others.1 11. Hopkins, W. A., in discussion on Scannell and Grillo.22 12. Likoff, W.; Geckeler, G. D., and Gregory, J. E.: Functional Mitral Stenosis Produced by an Intra-Atrial Tumor , Am. Heart J. 47:619, 1954.Crossref 13. Lyons, H. A.; Kelly, J. J., Jr.; Nusbaum, N., and Dennis, C.: Right Atrial Myxoma: A Clinical Study of a Patient in Whom Diagnosis Was Made by Angiocardiography During Life (Surgically Removed) , Am. J. Med. 25:321, 1958.Crossref 14. Mahaim, I.: Les tumeurs et les polypes du cœur: Étude anatamo-clinique , Paris, Masson & Cie, 1945. 15. Nichols, H. T.: The Removal of Benign Pedunculated Intra-Atrial Tumors: A Closed Surgical Approach , J. Thoracic Surg. 31:739, 1956. 16. Paquet, E.: The Diagnostic Approach to Auricular Myxomas , Canad. M. A. J. 74:121, 1956. 17. Prichard, R. W.: Tumors of the Heart: Review of the Subject and Report of 150 Cases , A. M. A. Arch. Path. 51:98, 1951. 18. Ravid, J. M., and Sachs, J.: Tumors of the Heart, with Report of Primary Fibromyxosarcoma of the Left Auricle and Pulmonary Vein, Associated with Multiple Tumors of the Mesentery and Gastrointestinal Tract , Am. Heart J. 26:385, 1943.Crossref 19. Ribbert, M. W. H.: Geschwulstlehre fiir Aerzte und Studierende , Bonn, F. Cohen, 1904, p. 230 20. Robertson, R., in discussion on Scannell and Grillo.22 21. Scannell, J. G., and Grillo, H. C.: Primary Tumors of the Heart, a Surgical Problem , J. Thoracic Surg. 35:23, 1958. 22. Steinberg, I.; Dotter, C. T., and Glenn, F.: Myxoma of Heart: Roentgen Diagnosis During Life in 3 Cases , Dis. Chest 24:509, 1953.Crossref 23. Stout, A. P.: Myxoma, the Tumor of Primitive Mesenchyme , Ann. Surg. 127:706, 1948.Crossref 24. Thorel, C.: Geschwülste des Herzens , ergebn. allg. Path. u. path. Anat. 17: ( (Pt. 2) ):677, 1915.

Journal

A.M.A. Archives SurgeryAmerican Medical Association

Published: Mar 1, 1959

References