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Carbohydrate Metabolism in Brain Disease: IX. Carbohydrate Metabolism in the Chronic Alcoholic Psychoses

Carbohydrate Metabolism in Brain Disease: IX. Carbohydrate Metabolism in the Chronic Alcoholic... Abstract Earlier work has shown that patients with schizophrenic, manic-depressive, and involutional psychoses have a disorder of carbohydrate metabolism 1 that is indistinguishable from one exhibited by nonpsychotic patients with a chronic brain disease, i. e., multiple sclerosis.2 The present report describes certain aspects of carbohydrate metabolism in another brain disease—chronic alcoholic psychosis. Actually, the patients discussed here constituted two groups: (a) those with Korsakoff's psychosis and (b) those with chronic auditory hallucinosis associated with alcoholism. Material and Methods Nine patients were studied; all were women. One group consisted of four patients, aged 31, 49, 60, and 62 years, respectively, with the classic features of Korsakoff's psychosis—impairment of memory, confabulation, and an inability to learn and retain newly presented material. All four patients had a background of serious alcoholism and still showed the stigmata of a previous attack of Wernicke's encephalopathy in the form of horizontal nystagmus and slight ataxia. References 1. Henneman, D. H.; Altschule, M. D., and Goncz, R. M.: Carbohydrate Metabolism in Brain Disease: II. Glucose Metabolism in Schizophrenic, Manic-Depressive, and Involutional Psychoses , A. M. A. Arch. Int. Med. 94:402-416, 1954.Crossref 2. Henneman, D. H.; Altschule, M. D.; Goncz, R. M., and Alexander, L.: Carbohydrate Metabolism in Brain Disease: I. Glucose Metabolism in Multiple Sclerosis , A. M. A. Arch. Neurol. & Psychiat. 72:688-695, 1954. 3. Victor, M., and Adams, R. D.: The Effect of Alcohol on the Nervous System , Proc. A. Res. Nerv. & Ment. Dis., Proc. ( (1952) ) 32:526-573, 1953. 4. Altschule, M. D.: Bodily Physiology in Mental and Emotional Disorders , New York, Grune & Stratton, Inc., 1953. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png A.M.A. Archives of Internal Medicine American Medical Association

Carbohydrate Metabolism in Brain Disease: IX. Carbohydrate Metabolism in the Chronic Alcoholic Psychoses

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References (6)

Publisher
American Medical Association
Copyright
Copyright © 1957 American Medical Association. All Rights Reserved.
ISSN
0888-2479
DOI
10.1001/archinte.1957.00260010042006
Publisher site
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Abstract

Abstract Earlier work has shown that patients with schizophrenic, manic-depressive, and involutional psychoses have a disorder of carbohydrate metabolism 1 that is indistinguishable from one exhibited by nonpsychotic patients with a chronic brain disease, i. e., multiple sclerosis.2 The present report describes certain aspects of carbohydrate metabolism in another brain disease—chronic alcoholic psychosis. Actually, the patients discussed here constituted two groups: (a) those with Korsakoff's psychosis and (b) those with chronic auditory hallucinosis associated with alcoholism. Material and Methods Nine patients were studied; all were women. One group consisted of four patients, aged 31, 49, 60, and 62 years, respectively, with the classic features of Korsakoff's psychosis—impairment of memory, confabulation, and an inability to learn and retain newly presented material. All four patients had a background of serious alcoholism and still showed the stigmata of a previous attack of Wernicke's encephalopathy in the form of horizontal nystagmus and slight ataxia. References 1. Henneman, D. H.; Altschule, M. D., and Goncz, R. M.: Carbohydrate Metabolism in Brain Disease: II. Glucose Metabolism in Schizophrenic, Manic-Depressive, and Involutional Psychoses , A. M. A. Arch. Int. Med. 94:402-416, 1954.Crossref 2. Henneman, D. H.; Altschule, M. D.; Goncz, R. M., and Alexander, L.: Carbohydrate Metabolism in Brain Disease: I. Glucose Metabolism in Multiple Sclerosis , A. M. A. Arch. Neurol. & Psychiat. 72:688-695, 1954. 3. Victor, M., and Adams, R. D.: The Effect of Alcohol on the Nervous System , Proc. A. Res. Nerv. & Ment. Dis., Proc. ( (1952) ) 32:526-573, 1953. 4. Altschule, M. D.: Bodily Physiology in Mental and Emotional Disorders , New York, Grune & Stratton, Inc., 1953.

Journal

A.M.A. Archives of Internal Medicine – American Medical Association

Published: Jan 1, 1957

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