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Capillary and Venous Bilirubin Values: They Are Different—and How!

Capillary and Venous Bilirubin Values: They Are Different—and How! Abstract Sir.—Leslie et al1 recently reported clinically significant differences between capillary and venous bilirubin values. We, too, have compared such paired samples2 and have also found significant differences, albeit in exactly the opposite direction, ie, higher values in capillary blood as opposed to the finding of Leslie et al that capillary blood levels underestimate venous levels. As our study differed as to both patient population and methodology, we wish to add our comments. In contrast to the study by Leslie et al, our study was limited only to clinically icteric infants who did not receive phototherapy. Simultaneously drawn paired samples of capillary and venous blood were obtained in random order from 20 infants and analyzed blindly by the Astra-8 (Beckman Instrument Corp Inc, Brea, Calif) autoanalyzer. The mean bilirubin level of the total capillary group was not significantly different than the mean of the venous sample group: References 1. Leslie GI, Phillips JB, Cassady G: Capillary and venous bilirubin values: Are they really different? AJDC 1987;141:1199-1200. 2. Schimmel MS, Algur N, Eidelman AI, et al: Capillary versus venous serum bilirubin measurements: A comparative study, (Hebrew) . Harefuah 1985;109:387. 3. Astra-8 Manual , Brea, Calif, Beckman Instrument Corp Inc, 1981. 4. Sherwin JE, Obernolte R: Bilirubin , in Pierce Aj, Kaplann LA (eds): Methods in Clinical Chemistry . St Louis, CV Mosby Co, 1987, pp 1105-1109. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Diseases of Children American Medical Association

Capillary and Venous Bilirubin Values: They Are Different—and How!

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Capillary and Venous Bilirubin Values: They Are Different—and How!

Abstract

Abstract Sir.—Leslie et al1 recently reported clinically significant differences between capillary and venous bilirubin values. We, too, have compared such paired samples2 and have also found significant differences, albeit in exactly the opposite direction, ie, higher values in capillary blood as opposed to the finding of Leslie et al that capillary blood levels underestimate venous levels. As our study differed as to both patient population and methodology, we wish to add our...
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References (5)

Publisher
American Medical Association
Copyright
Copyright © 1989 American Medical Association. All Rights Reserved.
ISSN
0002-922X
DOI
10.1001/archpedi.1989.02150180020007
Publisher site
See Article on Publisher Site

Abstract

Abstract Sir.—Leslie et al1 recently reported clinically significant differences between capillary and venous bilirubin values. We, too, have compared such paired samples2 and have also found significant differences, albeit in exactly the opposite direction, ie, higher values in capillary blood as opposed to the finding of Leslie et al that capillary blood levels underestimate venous levels. As our study differed as to both patient population and methodology, we wish to add our comments. In contrast to the study by Leslie et al, our study was limited only to clinically icteric infants who did not receive phototherapy. Simultaneously drawn paired samples of capillary and venous blood were obtained in random order from 20 infants and analyzed blindly by the Astra-8 (Beckman Instrument Corp Inc, Brea, Calif) autoanalyzer. The mean bilirubin level of the total capillary group was not significantly different than the mean of the venous sample group: References 1. Leslie GI, Phillips JB, Cassady G: Capillary and venous bilirubin values: Are they really different? AJDC 1987;141:1199-1200. 2. Schimmel MS, Algur N, Eidelman AI, et al: Capillary versus venous serum bilirubin measurements: A comparative study, (Hebrew) . Harefuah 1985;109:387. 3. Astra-8 Manual , Brea, Calif, Beckman Instrument Corp Inc, 1981. 4. Sherwin JE, Obernolte R: Bilirubin , in Pierce Aj, Kaplann LA (eds): Methods in Clinical Chemistry . St Louis, CV Mosby Co, 1987, pp 1105-1109.

Journal

American Journal of Diseases of Children – American Medical Association

Published: Jun 1, 1989

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