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Can We Protect Pregnant Women and Young Infants From COVID-19 Through Maternal Immunization?

Can We Protect Pregnant Women and Young Infants From COVID-19 Through Maternal Immunization? Opinion EDITORIAL Can We Protect Pregnant Women and Young Infants From COVID-19 Through Maternal Immunization? Flor M. Munoz, MD Infection with severe acute respiratory syndrome coronavi- The time available for antibody transfer is another impor- rus 2 (SARS-CoV-2) during pregnancy and early infancy can re- tant factor. Flannery et al were able to ascertain that placen- 1-3 sult in severe disease. Less is known about the immune re- tal transfer ratios increased when the time between maternal sponses of pregnant women with coronavirus disease 2019 infection and delivery was longer. This finding is consistent (COVID-19) and the possibil- with similar observations on the transfer of antibodies in re- ity for infant protection. Vac- cent studies of a respiratory syncytial virus vaccine given dur- Related article page 594 cination of pregnant women ing pregnancy, where an interval of 30 days or more from vac- with SARS-CoV-2 vaccines in development has begun in the cination to delivery was significantly associated with higher United States in the context of emergency use authorized vac- antibody transfer. Interestingly, the transfer ratio of SARS- cine deployment for high-risk priority groups and guidance CoV-2 antibodies was not affected by premature delivery (ges- from the US Centers http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Pediatrics American Medical Association

Can We Protect Pregnant Women and Young Infants From COVID-19 Through Maternal Immunization?

JAMA Pediatrics , Volume 175 (6) – Jun 29, 2021

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References (19)

Publisher
American Medical Association
Copyright
Copyright 2021 American Medical Association. All Rights Reserved.
ISSN
2168-6203
eISSN
2168-6211
DOI
10.1001/jamapediatrics.2021.0043
Publisher site
See Article on Publisher Site

Abstract

Opinion EDITORIAL Can We Protect Pregnant Women and Young Infants From COVID-19 Through Maternal Immunization? Flor M. Munoz, MD Infection with severe acute respiratory syndrome coronavi- The time available for antibody transfer is another impor- rus 2 (SARS-CoV-2) during pregnancy and early infancy can re- tant factor. Flannery et al were able to ascertain that placen- 1-3 sult in severe disease. Less is known about the immune re- tal transfer ratios increased when the time between maternal sponses of pregnant women with coronavirus disease 2019 infection and delivery was longer. This finding is consistent (COVID-19) and the possibil- with similar observations on the transfer of antibodies in re- ity for infant protection. Vac- cent studies of a respiratory syncytial virus vaccine given dur- Related article page 594 cination of pregnant women ing pregnancy, where an interval of 30 days or more from vac- with SARS-CoV-2 vaccines in development has begun in the cination to delivery was significantly associated with higher United States in the context of emergency use authorized vac- antibody transfer. Interestingly, the transfer ratio of SARS- cine deployment for high-risk priority groups and guidance CoV-2 antibodies was not affected by premature delivery (ges- from the US Centers

Journal

JAMA PediatricsAmerican Medical Association

Published: Jun 29, 2021

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