ORIGINAL CONTRIBUTION Caloric Sweetener Consumption and Dyslipidemia Among US Adults Jean A. Welsh, MPH, RN Context Dietary carbohydrates have been associated with dyslipidemia, a lipid pro- file known to increase cardiovascular disease risk. Added sugars (caloric sweeteners Andrea Sharma, PhD, MPH used as ingredients in processed or prepared foods) are an increasing and potentially Jerome L. Abramson, PhD modifiable component in the US diet. No known studies have examined the associa- Viola Vaccarino, MD, PhD tion between the consumption of added sugars and lipid measures. Cathleen Gillespie, MS Objective To assess the association between consumption of added sugars and blood lipid levels in US adults. Miriam B. Vos, MD, MSPH Design, Setting, and Participants Cross-sectional study among US adults (n=6113) NCREASED CARBOHYDRATE CON- from the National Health and Nutrition Examination Survey (NHANES) 1999-2006. sumption has been associated with Respondents were grouped by intake of added sugars using limits specified in dietary lower high-density lipoprotein cho- recommendations (5% [reference group], 5%-10%, 10%-17.5%, 17.5%- 25%, and 25% of total calories). Linear regression was used to estimate adjusted Ilesterol (HDL-C) levels, higher tri- mean lipid levels. Logistic regression was used to determine adjusted odds ratios of glyceride levels, and higher low- dyslipidemia.
JAMA – American Medical Association
Published: Apr 21, 2010