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California Encephalitis in Children

California Encephalitis in Children Abstract The California group of arboviruses are now recognized as a significant cause of encephalitis in children. Fifty children with California encephalitis were seen at Columbus Children's Hospital between 1966 and 1970. The illness characteristically began abruptly with fever, lethargy, vomiting, and progressive encephalitic findings during the first two to four days and with recovery in seven to ten days. Focal neurologic findings were present in 20% and electroencephalograms revealed asymmetrical delta-wave activity in 40% of the children during the acute phase of the illness. References 1. Reeves WC, Hammon WMcD: California encephalitis virus, a newly described agent: III. Mosquito infection and transmission . J Immun 69:511-514, 1952. 2. Hammon WMcD, Reeves WC: California encephalitis virus, a newly described agent: I. Evidence of natural infection in man and other animals . Calif Med 77:303-309, 1952. 3. Thompson WH, Kalfayan B, Anslow RO: Isolation of California encephalitis group virus from a fatal human illness . Amer J Epidem 81:245-253, 1965. 4. Cramblett HG, Stegmiller H, Spencer C: California encephalitis virus infections in children: Laboratory and clinical studies . JAMA 198:108-112, 1966.Crossref 5. Clarke DH, Casals J: Techniques for hemagglutination and hemagglutination inhibition with arthropod-borne viruses . Amer J Trop Med 7:561-573, 1958. 6. Sever JL: Application of a microtechnique to viral serologic investigations . J Immun 88:320-329, 1962. 7. Diagnostic Complement Fixation Method (LBCF) , CDC Laboratory Branch training manual. US Dept of Health, Education, and Welfare, Public Health Service, 1962. 8. Henderson BE, Coleman PH: The growing importance of California arboviruses in the etiology of human disease . Progr Med Virol 13:405-461, 1971. 9. Masterson RA, Stegmiller HW, Parsons MA, et al: California encephalitis—an endemic puzzle in Ohio . Health Lab Sci 8:89-96, 1971. 10. Chun RWM, Thompson WH, Grabow JD, et al: California arbovirus encephalitis in children . Neurology 18:369-375, 1968.Crossref 11. Grabow JD, Matthews CG, Chun RWM, et al: The electroencephalogram and clinical sequelae of California arbovirus encephalitis . Neurology 19:394-404, 1969.Crossref 12. Young DJ: California encephalitis virus: Report of three cases and review of the literature . Ann Intern Med 65:419-428, 1966.Crossref 13. Quick DT, Smith AG, Lewis AL, et al: California encephalitis virus infection: A case report . Amer J Trop Med 14:456-459, 1965. 14. Johnson KP, Lepow ML, Johnson RT: California encephalitis: I. Clinical and epidemiologic studies . Neurology 18:250-254, 1968.Crossref 15. Gates EH, Bond JO, Lewis AL: California group arbovirus encephalitis in Florida children . J Fla Med Assoc 55:37-40, 1968. 16. Haynes RE, Cramblett HG, Kronfol HJ: Echovirus 9 meningoencephalitis in infants and children . JAMA 208:1657-1660, 1969.Crossref 17. Azimi PH, Cramblett HG, Haynes RE: Mumps meningoencephalitis in children . JAMA 207:509-512, 1969.Crossref 18. Haynes RE, Azimi PH, Cramblett HG: Fatal herpesvirus hominis (herpes simplex virus) infections in children . JAMA 206:312-319, 1968.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Diseases of Children American Medical Association

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Publisher
American Medical Association
Copyright
Copyright © 1972 American Medical Association. All Rights Reserved.
ISSN
0002-922X
DOI
10.1001/archpedi.1972.02110160068006
Publisher site
See Article on Publisher Site

Abstract

Abstract The California group of arboviruses are now recognized as a significant cause of encephalitis in children. Fifty children with California encephalitis were seen at Columbus Children's Hospital between 1966 and 1970. The illness characteristically began abruptly with fever, lethargy, vomiting, and progressive encephalitic findings during the first two to four days and with recovery in seven to ten days. Focal neurologic findings were present in 20% and electroencephalograms revealed asymmetrical delta-wave activity in 40% of the children during the acute phase of the illness. References 1. Reeves WC, Hammon WMcD: California encephalitis virus, a newly described agent: III. Mosquito infection and transmission . J Immun 69:511-514, 1952. 2. Hammon WMcD, Reeves WC: California encephalitis virus, a newly described agent: I. Evidence of natural infection in man and other animals . Calif Med 77:303-309, 1952. 3. Thompson WH, Kalfayan B, Anslow RO: Isolation of California encephalitis group virus from a fatal human illness . Amer J Epidem 81:245-253, 1965. 4. Cramblett HG, Stegmiller H, Spencer C: California encephalitis virus infections in children: Laboratory and clinical studies . JAMA 198:108-112, 1966.Crossref 5. Clarke DH, Casals J: Techniques for hemagglutination and hemagglutination inhibition with arthropod-borne viruses . Amer J Trop Med 7:561-573, 1958. 6. Sever JL: Application of a microtechnique to viral serologic investigations . J Immun 88:320-329, 1962. 7. Diagnostic Complement Fixation Method (LBCF) , CDC Laboratory Branch training manual. US Dept of Health, Education, and Welfare, Public Health Service, 1962. 8. Henderson BE, Coleman PH: The growing importance of California arboviruses in the etiology of human disease . Progr Med Virol 13:405-461, 1971. 9. Masterson RA, Stegmiller HW, Parsons MA, et al: California encephalitis—an endemic puzzle in Ohio . Health Lab Sci 8:89-96, 1971. 10. Chun RWM, Thompson WH, Grabow JD, et al: California arbovirus encephalitis in children . Neurology 18:369-375, 1968.Crossref 11. Grabow JD, Matthews CG, Chun RWM, et al: The electroencephalogram and clinical sequelae of California arbovirus encephalitis . Neurology 19:394-404, 1969.Crossref 12. Young DJ: California encephalitis virus: Report of three cases and review of the literature . Ann Intern Med 65:419-428, 1966.Crossref 13. Quick DT, Smith AG, Lewis AL, et al: California encephalitis virus infection: A case report . Amer J Trop Med 14:456-459, 1965. 14. Johnson KP, Lepow ML, Johnson RT: California encephalitis: I. Clinical and epidemiologic studies . Neurology 18:250-254, 1968.Crossref 15. Gates EH, Bond JO, Lewis AL: California group arbovirus encephalitis in Florida children . J Fla Med Assoc 55:37-40, 1968. 16. Haynes RE, Cramblett HG, Kronfol HJ: Echovirus 9 meningoencephalitis in infants and children . JAMA 208:1657-1660, 1969.Crossref 17. Azimi PH, Cramblett HG, Haynes RE: Mumps meningoencephalitis in children . JAMA 207:509-512, 1969.Crossref 18. Haynes RE, Azimi PH, Cramblett HG: Fatal herpesvirus hominis (herpes simplex virus) infections in children . JAMA 206:312-319, 1968.Crossref

Journal

American Journal of Diseases of ChildrenAmerican Medical Association

Published: Oct 1, 1972

References