Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

CALCIUM CONTENT OF THE BRAIN AND ITS DISTRIBUTION IN VARIOUS REGIONS DURING DIALLYLBARBITURIC ACID NARCOSIS: AN EXPERIMENTAL STUDY

CALCIUM CONTENT OF THE BRAIN AND ITS DISTRIBUTION IN VARIOUS REGIONS DURING DIALLYLBARBITURIC... Abstract Previous calcium studies in sleep have led to the conclusion that hypnotic sleep provoked by diallylbarbituric acid is associated with a decrease of calcium in both blood and cerebrospinal fluid.1 This experimental investigation is concerned with the calcium content of the brain and also specifically with the distribution of calcium in certain areas of the brain in a series of animals killed during sleep and in another series killed in the waking state. Calcium has been chosen as the subject of study in preference to other blood constituents on account of the investigations referring to its pharmacodynamic effect on the brain and to the particular rôle it is alleged to play in sleep. Pharmacologic studies, among which those concerned with calcium are preeminent, have contributed greatly to the much debated problem as to whether sleep is regulated by specific sleep centers. The common character of these pharmacologic contributions lies References 1. Katzenelbogen, S.: The Blood Electrolyte Changes in Narcosis, with Special Reference to Calcium and Potassium: An Experimental Study , Arch. Neurol. & Psychiat. 24:525 ( (Sept.) ) 1930 2. The Distribution of Calcium Between Blood and Cerebrospinal Fluid in Sleep Induced by Diallylbarbituric Acid: An Experimental Study , Katzenelbogen Arch. Neurol. & Psychiat. 27:154 ( (Jan.) ) 1932. 3. Mehes, J.: Studien über den Angriffspunct von Schlafmitteln , Wien. klin. Wchnschr. 39:962, 1926. 4. Pick, E. P.: Pharmakologie des vegetativen Nervensystems , Deutsche Ztschr. f. Nervenh. 106:238, 1928. 5. Morita, S.: Untersuchungen an grosshirnlosen Kaninchen , Arch. f. exper. Path. u. Pharmakol. 78:208, 218 and 223, 1915. 6. Airila: Arch. internat. de pharmacodyn. et de thérapie 23:453, 1913. 7. Pick (footnote 3). 8. Morita (footnote 4). 9. Keeser, E., and Keeser, T.: Ueber die Lokalisation des Veronals, des Phenyläthyl und Diallylbarbitursäure im Gehirn , Arch. f. exper. Path. u. Pharmakol. 125:251, 1927 10. Ueber den Nachweis von Caffein, Morphin und Barbitursäure Derivaten im Gehirn , Keeser Arch. f. exper. Path. u. Pharmakol. 127:230, 1927. 11. Pick, E. P.: Ueber Schlaf und Schlafmittel , Wien. klin. Wchnschr. 40: 634, 1927. 12. Molitor, H., and Pick, E. P.: Verstaerkte Schlafmittel-Wirkung durch gleichzeitige Behandlung verschiedener Hirnteile , Arch. f. exper. Path. u. Pharmakol. 115:318, 1926. 13. Mansfield: Experimental Investigation on the Nature and Promises of Tetany Therapy with Magnesium Sulphate , München. med. Wchnschr. 62:208, 1915. 14. Demole, V.: Pharmakologisch-anatomische Untersuchungen zum Problem des Schlafes , Arch. f. exper. Path. u. Pharmakol. 120:229, 1927. 15. Cloetta and Thomann: Chemisch-physikalische Untersuchungen zur Theorie der Narkose , Arch. f. exper. Path. u. Pharmakol. 103:260, 1924. 16. Hess, W. R.: Ueber die Wechselbeziehungen zwischen psychischen und vegetativen Funktionen , Schweiz. Arch. f. Neurol. u. Psychiat. 16:35 and 285, 1925. 17. Hess, W. R.: Die Funktionen des vegetativen Nervensystems , Klin. Wchnschr. 9:1009, 1930. 18. Righetti, R.: Contributo clinico e anatomo-patologico allo studio dei gliomi cerebrali , Riv. di pat. nerv. 8:241, 1903. 19. Weisenburg, T. H.: Tumors of the Third Ventricle, with the Establishment of a Symptom-Complex , Brain 33:236, 1911. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Neurology & Psychiatry American Medical Association

CALCIUM CONTENT OF THE BRAIN AND ITS DISTRIBUTION IN VARIOUS REGIONS DURING DIALLYLBARBITURIC ACID NARCOSIS: AN EXPERIMENTAL STUDY

Archives of Neurology & Psychiatry , Volume 28 (2) – Aug 1, 1932

Loading next page...
 
/lp/american-medical-association/calcium-content-of-the-brain-and-its-distribution-in-various-regions-9yTk989hob
Publisher
American Medical Association
Copyright
Copyright © 1932 American Medical Association. All Rights Reserved.
ISSN
0096-6754
DOI
10.1001/archneurpsyc.1932.02240020157012
Publisher site
See Article on Publisher Site

Abstract

Abstract Previous calcium studies in sleep have led to the conclusion that hypnotic sleep provoked by diallylbarbituric acid is associated with a decrease of calcium in both blood and cerebrospinal fluid.1 This experimental investigation is concerned with the calcium content of the brain and also specifically with the distribution of calcium in certain areas of the brain in a series of animals killed during sleep and in another series killed in the waking state. Calcium has been chosen as the subject of study in preference to other blood constituents on account of the investigations referring to its pharmacodynamic effect on the brain and to the particular rôle it is alleged to play in sleep. Pharmacologic studies, among which those concerned with calcium are preeminent, have contributed greatly to the much debated problem as to whether sleep is regulated by specific sleep centers. The common character of these pharmacologic contributions lies References 1. Katzenelbogen, S.: The Blood Electrolyte Changes in Narcosis, with Special Reference to Calcium and Potassium: An Experimental Study , Arch. Neurol. & Psychiat. 24:525 ( (Sept.) ) 1930 2. The Distribution of Calcium Between Blood and Cerebrospinal Fluid in Sleep Induced by Diallylbarbituric Acid: An Experimental Study , Katzenelbogen Arch. Neurol. & Psychiat. 27:154 ( (Jan.) ) 1932. 3. Mehes, J.: Studien über den Angriffspunct von Schlafmitteln , Wien. klin. Wchnschr. 39:962, 1926. 4. Pick, E. P.: Pharmakologie des vegetativen Nervensystems , Deutsche Ztschr. f. Nervenh. 106:238, 1928. 5. Morita, S.: Untersuchungen an grosshirnlosen Kaninchen , Arch. f. exper. Path. u. Pharmakol. 78:208, 218 and 223, 1915. 6. Airila: Arch. internat. de pharmacodyn. et de thérapie 23:453, 1913. 7. Pick (footnote 3). 8. Morita (footnote 4). 9. Keeser, E., and Keeser, T.: Ueber die Lokalisation des Veronals, des Phenyläthyl und Diallylbarbitursäure im Gehirn , Arch. f. exper. Path. u. Pharmakol. 125:251, 1927 10. Ueber den Nachweis von Caffein, Morphin und Barbitursäure Derivaten im Gehirn , Keeser Arch. f. exper. Path. u. Pharmakol. 127:230, 1927. 11. Pick, E. P.: Ueber Schlaf und Schlafmittel , Wien. klin. Wchnschr. 40: 634, 1927. 12. Molitor, H., and Pick, E. P.: Verstaerkte Schlafmittel-Wirkung durch gleichzeitige Behandlung verschiedener Hirnteile , Arch. f. exper. Path. u. Pharmakol. 115:318, 1926. 13. Mansfield: Experimental Investigation on the Nature and Promises of Tetany Therapy with Magnesium Sulphate , München. med. Wchnschr. 62:208, 1915. 14. Demole, V.: Pharmakologisch-anatomische Untersuchungen zum Problem des Schlafes , Arch. f. exper. Path. u. Pharmakol. 120:229, 1927. 15. Cloetta and Thomann: Chemisch-physikalische Untersuchungen zur Theorie der Narkose , Arch. f. exper. Path. u. Pharmakol. 103:260, 1924. 16. Hess, W. R.: Ueber die Wechselbeziehungen zwischen psychischen und vegetativen Funktionen , Schweiz. Arch. f. Neurol. u. Psychiat. 16:35 and 285, 1925. 17. Hess, W. R.: Die Funktionen des vegetativen Nervensystems , Klin. Wchnschr. 9:1009, 1930. 18. Righetti, R.: Contributo clinico e anatomo-patologico allo studio dei gliomi cerebrali , Riv. di pat. nerv. 8:241, 1903. 19. Weisenburg, T. H.: Tumors of the Third Ventricle, with the Establishment of a Symptom-Complex , Brain 33:236, 1911.

Journal

Archives of Neurology & PsychiatryAmerican Medical Association

Published: Aug 1, 1932

References