Burden of Neurological Disorders Across the US From 1990-2017

Burden of Neurological Disorders Across the US From 1990-2017 Key PointsQuestionWhat is the current burden of neurological disorders in the US by states, and what are the temporal trends (from 1990 to 2017)? FindingsSystematic analysis of the Global Burden of Disease study shows that, in 2017, the 3 most burdensome neurological disorders in the US were stroke, Alzheimer disease and other dementias, and migraine. The burden of individual neurological disorders varied moderately to widely by states (a 1.2-fold to 7.5-fold difference), and the absolute numbers of incident, prevalent, and fatal cases and disability-adjusted life-years of neurological disorders (except for traumatic brain injury incidence; spinal cord injury prevalence; meningitis prevalence, deaths, and disability-adjusted life-years; and encephalitis disability-adjusted life-years) across all US states increased from 1990 to 2017. MeaningA large and increasing number of people have various neurological disorders in the US, with significant variation in the burden of and trends in neurological disorders across the US states, and the reasons for these geographic variations need to be explored further. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Neurology American Medical Association

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Publisher
American Medical Association
Copyright
Copyright 2020 GBD 2017 US Neurological Disorders Collaborators. JAMA Neurology.
ISSN
2168-6149
eISSN
2168-6157
DOI
10.1001/jamaneurol.2020.4152
Publisher site
See Article on Publisher Site

Abstract

Key PointsQuestionWhat is the current burden of neurological disorders in the US by states, and what are the temporal trends (from 1990 to 2017)? FindingsSystematic analysis of the Global Burden of Disease study shows that, in 2017, the 3 most burdensome neurological disorders in the US were stroke, Alzheimer disease and other dementias, and migraine. The burden of individual neurological disorders varied moderately to widely by states (a 1.2-fold to 7.5-fold difference), and the absolute numbers of incident, prevalent, and fatal cases and disability-adjusted life-years of neurological disorders (except for traumatic brain injury incidence; spinal cord injury prevalence; meningitis prevalence, deaths, and disability-adjusted life-years; and encephalitis disability-adjusted life-years) across all US states increased from 1990 to 2017. MeaningA large and increasing number of people have various neurological disorders in the US, with significant variation in the burden of and trends in neurological disorders across the US states, and the reasons for these geographic variations need to be explored further.

Journal

JAMA NeurologyAmerican Medical Association

Published: Feb 2, 2021

References

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