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Bronchoesophagology

Bronchoesophagology The endoscopic aspects of both primary and secondary tuberculosis in children and adults received unusual attention in 1958, and the reports on endobronchial involvement in primary infections of childhood were noteworthy. Observations on esophagitis and hiatus hernia continued to predominate in the literature on esophagology, and even though considerable basic research was carried out on the esophagogastric sphincter the exact mechanism remains unsettled. Experimental Studies Utilizing the blood level of dogs, Adriani and Campbell1 undertook to determine the absorption rate of topically applied tetracaine and cocaine. Blood levels were obtained after topical application of the drugs in the pyriform fossa, the trachea, and the bronchi and after rapid I.V. injection, slow I.V. injection, and infiltration into subcutaneous tissue. The quantity of drug which resulted in no detectable blood level when infiltrated subcutaneously gave levels when topically applied equal to one-third to one-half of those after rapid I.V. injection. Epinephrine http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Otolaryngolog American Medical Association

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Publisher
American Medical Association
Copyright
Copyright © 1960 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0003-9977
eISSN
1538-361X
DOI
10.1001/archotol.1960.00740010261020
Publisher site
See Article on Publisher Site

Abstract

The endoscopic aspects of both primary and secondary tuberculosis in children and adults received unusual attention in 1958, and the reports on endobronchial involvement in primary infections of childhood were noteworthy. Observations on esophagitis and hiatus hernia continued to predominate in the literature on esophagology, and even though considerable basic research was carried out on the esophagogastric sphincter the exact mechanism remains unsettled. Experimental Studies Utilizing the blood level of dogs, Adriani and Campbell1 undertook to determine the absorption rate of topically applied tetracaine and cocaine. Blood levels were obtained after topical application of the drugs in the pyriform fossa, the trachea, and the bronchi and after rapid I.V. injection, slow I.V. injection, and infiltration into subcutaneous tissue. The quantity of drug which resulted in no detectable blood level when infiltrated subcutaneously gave levels when topically applied equal to one-third to one-half of those after rapid I.V. injection. Epinephrine

Journal

Archives of OtolaryngologAmerican Medical Association

Published: Aug 1, 1960

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