Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Breast Erythema and Induration in a 77-Year-Old Woman—Quiz Case

Breast Erythema and Induration in a 77-Year-Old Woman—Quiz Case Report of a case A 77-year-old woman presented with a 10-month history of nontender, nonprogressive erythema and induration of the left breast that she had first noticed 4 months after she had completed a course of radiotherapy following a lumpectomy and chemotherapy for a 3-cm, poorly differentiated, infiltrating ductal carcinoma of the left breast. The tumor was found to be stage IIB, with 2 axillary sentinel nodes that were positive for metastases, which had been identified only on immunohistochemical analysis. There was no evidence of systemic metastases. The tumor was estrogen receptor negative and progesterone receptor positive. The patient received 4 cycles of doxorubicin and cyclophosphamide, followed by a course of external beam irradiation to the tumor bed (4678 rad [46.8 Gy] in 26 fractions over 37 days, followed by a 1400-rad [14.0-Gy] boost in 7 fractions over 13 days). She had no history of carcinoma or radiotherapy. Skin examination showed a large, erythematous, indurated plaque and focal areas with a peau d’orange appearance; the plaque was confined to the radiation field of the left breast (Figure 1). No masses or lymphadenopathy was noted. An incisional biopsy specimen was obtained (Figure 2 and Figure 3). Figure 1. View LargeDownload Figure 2. View LargeDownload Figure 3. View LargeDownload What is your diagnosis? http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

Breast Erythema and Induration in a 77-Year-Old Woman—Quiz Case

Breast Erythema and Induration in a 77-Year-Old Woman—Quiz Case

Abstract

Report of a case A 77-year-old woman presented with a 10-month history of nontender, nonprogressive erythema and induration of the left breast that she had first noticed 4 months after she had completed a course of radiotherapy following a lumpectomy and chemotherapy for a 3-cm, poorly differentiated, infiltrating ductal carcinoma of the left breast. The tumor was found to be stage IIB, with 2 axillary sentinel nodes that were positive for metastases, which had been identified only on...
Loading next page...
 
/lp/american-medical-association/breast-erythema-and-induration-in-a-77-year-old-woman-quiz-case-zKxIa6yQEE
Publisher
American Medical Association
Copyright
Copyright © 2006 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.142.1.101-c
Publisher site
See Article on Publisher Site

Abstract

Report of a case A 77-year-old woman presented with a 10-month history of nontender, nonprogressive erythema and induration of the left breast that she had first noticed 4 months after she had completed a course of radiotherapy following a lumpectomy and chemotherapy for a 3-cm, poorly differentiated, infiltrating ductal carcinoma of the left breast. The tumor was found to be stage IIB, with 2 axillary sentinel nodes that were positive for metastases, which had been identified only on immunohistochemical analysis. There was no evidence of systemic metastases. The tumor was estrogen receptor negative and progesterone receptor positive. The patient received 4 cycles of doxorubicin and cyclophosphamide, followed by a course of external beam irradiation to the tumor bed (4678 rad [46.8 Gy] in 26 fractions over 37 days, followed by a 1400-rad [14.0-Gy] boost in 7 fractions over 13 days). She had no history of carcinoma or radiotherapy. Skin examination showed a large, erythematous, indurated plaque and focal areas with a peau d’orange appearance; the plaque was confined to the radiation field of the left breast (Figure 1). No masses or lymphadenopathy was noted. An incisional biopsy specimen was obtained (Figure 2 and Figure 3). Figure 1. View LargeDownload Figure 2. View LargeDownload Figure 3. View LargeDownload What is your diagnosis?

Journal

Archives of DermatologyAmerican Medical Association

Published: Jan 1, 2006

Keywords: erythema,breast

There are no references for this article.